Mutations in the CLCN2 gene are a rare cause of idiopathic generalized epilepsy syndromes

被引：0
|
作者：
E. Stogmann
P. Lichtner
C. Baumgartner
M. Schmied
C. Hotzy
F. Asmus
F. Leutmezer
S. Bonelli
E. Assem-Hilger
K. Vass
K. Hatala
T. M. Strom
T. Meitinger
F. Zimprich
A. Zimprich
机构：
[1] Medical University of Vienna,Department of Neurology
[2] Allgemeines Krankenhaus Stadt Wien,Institute of Human Genetics
[3] GSF National Research Centre for Environment and Health,Department of Neurodegenerative Diseases
[4] Hertie Institute for Clinical Brain Research,Institute of Human Genetics
[5] Technical University Munich,undefined
来源：
Neurogenetics | 2006年 / 7卷
关键词：
CLCN2; Idiopathic generalized epilepsy;
D O I：
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中图分类号：
学科分类号：
摘要：
Mutations in the chloride channel gene CLCN2 have been reported in families with generalized and focal epilepsy syndromes. To evaluate the contribution of mutations in the CLCN2 gene to the etiology of epilepsies in our population, we screened 96 patients with different epilepsy syndromes and a putative genetic background. No definite mutations were found in our study population. We conclude that mutations in the CLCN2 gene are only a rare cause of idiopathic generalized epilepsy.
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页码：265 / 268
页数：3
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