K-80003 Inhibition of Macrophage Apoptosis and Necrotic Core Development in Atherosclerotic Vulnerable Plaques

被引：0
|
作者：
Xiaolei Wang
Zhe Sun
Ruosen Yuan
Weifeng Zhang
Yejiao Shen
Anwen Yin
Yanjie Li
Qingqi Ji
Xia Wang
Yi Li
Min Zhang
Xin Pan
Linghong Shen
Ben He
机构：
[1] Shanghai Jiao Tong University,Department of Cardiology, Shanghai Chest Hospital
[2] Xuhui Distinct,School of Life Science and Technology
[3] Shanghai Tech University,undefined
来源：
Cardiovascular Drugs and Therapy | 2022年 / 36卷
关键词：
Apoptosis; Macrophage; Autophagy; Oxidative stress; Vulnerable plaque;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1061 / 1073
页数：12
相关论文
共 50 条
  • [41] Leukocyte cathepsin S deficiency attenuates macrophage cell death, necrotic core formation and collagen deposition in advanced plaques of LDLr knockout mice
    De Nooijer, R
    von der Thuesen, JH
    Piket, B
    Leeuwenburgh, MA
    Jukema, WJ
    van der Wall, EE
    van Berkel, TJ
    Shi, GP
    Biessen, EA
    CIRCULATION, 2005, 112 (17) : U165 - U165
  • [42] Simvastatin Suppresses Apoptosis in Vulnerable Atherosclerotic Plaques Through Regulating the Expression of p53, Bcl-2 and Bcl-xL
    Weiwei Qin
    Yonggang Lu
    Chengyan Zhan
    Tao Shen
    Lin Dou
    Yong Man
    Shu Wang
    Chuanshi Xiao
    Yunfei Bian
    Jian Li
    Cardiovascular Drugs and Therapy, 2012, 26 : 23 - 30
  • [43] Simvastatin Suppresses Apoptosis in Vulnerable Atherosclerotic Plaques Through Regulating the Expression of p53, Bcl-2 and Bcl-xL
    Qin, Weiwei
    Lu, Yonggang
    Zhan, Chengyan
    Shen, Tao
    Dou, Lin
    Man, Yong
    Wang, Shu
    Xiao, Chuanshi
    Bian, Yunfei
    Li, Jian
    CARDIOVASCULAR DRUGS AND THERAPY, 2012, 26 (01) : 23 - 30
  • [44] Cytotoxic and Proinflammatory CD8+ T Lymphocytes Promote Development of Vulnerable Atherosclerotic Plaques in ApoE-Deficient Mice
    Kyaw, Tin
    Winship, Amy
    Tay, Christopher
    Kanellakis, Peter
    Hosseini, Hamid
    Cao, Anh
    Li, Priscilla
    Tipping, Peter
    Bobik, Alex
    Toh, Ban-Hock
    CIRCULATION, 2013, 127 (09) : 1028 - +
  • [45] In Vivo and Ex Vivo Measurements of the Mean ADC Values of Lipid Necrotic Core and Hemorrhage Obtained From Diffusion Weighted Imaging in Human Atherosclerotic Plaques
    Kim, Seong-Eun
    Treiman, Gerald S.
    Roberts, John A.
    Jeong, Eun-Kee
    Shi, Xianfeng
    Hadley, J. Rock
    Parker, Dennis L.
    JOURNAL OF MAGNETIC RESONANCE IMAGING, 2011, 34 (05) : 1167 - 1175
  • [46] Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic plaques of LDLR deficient mice
    Yu, Pei
    Qian, Alexander S.
    Chathely, Kevin M.
    Trigatti, Bernardo L.
    DATA IN BRIEF, 2018, 19 : 1148 - 1161
  • [47] Reflectance, Fluorescence, and Raman Spectroscopy Identify Features of Vulnerable Atherosclerotic Plaque In Vivo Including a Thin Fibrous Cap, Necrotic Core or Superficial Foam Cells, and Thrombus
    Scepanovic, Obrad R.
    Fitzmaurice, Maryann
    Miller, Arnold
    Kong, Chae-Ryon
    Dasari, Ramachandra R.
    Kramer, John R.
    Feld, Michael S.
    CIRCULATION, 2008, 118 (18) : S746 - S747
  • [48] Role of macrophage and smooth muscle cell apoptosis in association with oxidized low-density lipoprotein in the atherosclerotic development
    Akishima, Y
    Akasaka, Y
    Ishikawa, Y
    Lijun, Z
    Kiguchi, H
    Ito, K
    Itabe, H
    Ishii, T
    MODERN PATHOLOGY, 2005, 18 (03) : 365 - 373
  • [49] The Protein Synthesis Inhibitor Anisomycin Induces Macrophage Apoptosis in Rabbit Atherosclerotic Plaques through p38 Mitogen-Activated Protein Kinase
    Croons, Valerie
    Martinet, Wim
    Herman, Arnold G.
    Timmermans, Jean-Pierre
    De Meyer, Guido R. Y.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2009, 329 (03): : 856 - 864
  • [50] MicroRNA-202-5p-dependent inhibition of Bcl-2 contributes to macrophage apoptosis and atherosclerotic plaque formation
    Xu, Fei
    Yao, Fang
    Ning, Yayuan
    GENE, 2023, 867
12345