Current practice and evolving concepts in septic shock resuscitation

被引：0

作者：

Jan Bakker

Eduardo Kattan

Djillali Annane

Ricardo Castro

Maurizio Cecconi

Daniel De Backer

Arnaldo Dubin

Laura Evans

Michelle Ng Gong

Olfa Hamzaoui

Can Ince

Bruno Levy

Xavier Monnet

Gustavo A. Ospina Tascón

Marlies Ostermann

Michael R. Pinsky

James A. Russell

Bernd Saugel

Thomas W. L. Scheeren

Jean-Louis Teboul

Antoine Vieillard Baron

Jean-Louis Vincent

Fernando G. Zampieri

Glenn Hernandez

机构：

[1] Erasmus MC University Medical Center,Department of Intensive Care

[2] Columbia University Medical Center,Department of Pulmonology and Critical Care

[3] NYU School of Medicinel Langone,Departamento de Medicina Intensiva, Facultad de Medicina

[4] Pontificia Universidad Católica de Chile,Intensive Care Unit

[5] Hôpital Raymond-Poincaré,AP

[6] UFR des Sciences de la Santé Simone-Veil,HP

[7] Université de Versailles Saint-Quentin-en-Yvelines,Department of Biomedical Sciences

[8] Humanitas University Pieve Emanuele,Department of Anesthesia and Intensive Care

[9] IRCCS Humanitas Research Hospital,Department of Intensive Care, CHIREC Hospitals

[10] Université Libre de Bruxelles,Cátedra de Farmacología Aplicada, Facultad de Ciencias Médicas

[11] Universidad Nacional de La Plata,Department of Pulmonary and Critical Care Medicine

[12] Sanatorio Otamendi,Division of Critical Care Medicine, Division of Pulmonary Medicine, Department of Medicine

[13] University of Washington,Service de Réanimation Polyvalente

[14] Montefiore Healthcare System/Albert Einstein College of Medicine,Service de Réanimation Médicale Brabois

[15] Hôpital Antoine Béclère,Service de médecine intensive

[16] AP-HP,réanimation, Hôpital de Bicêtre, DMU CORREVE, Inserm UMR S_999, FHU SEPSIS, Groupe de Recherche Clinique CARMAS

[17] Université Paris-Saclay,Department of Intensive Care Medicine Fundación Valle del Lili

[18] CHRU Nancy,Department of Critical Care

[19] Pôle Cardio-Médico-Chirurgical,Department Bioengineering, Anesthesiology and Cardiovascular Diseases, Department of Critical Care Medicine

[20] INSERM U1116,Centre for Heart Lung Innovation

[21] Faculté de Médecine,Department of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine

[22] Université de Lorraine,Department of Anesthesiology

[23] Université Paris-Saclay,Service de Médecine Intensive

[24] AP-HP,Réanimation, Hôpital Bicêtre

[25] Universidad ICESI,Medical Intensive Care Unit

[26] King’s College London,INSERM UMR 1018, Clinical Epidemiology Team, CESP

[27] Guy’s and St Thomas’ NHS Foundation Trust,Dept of Intensive Care

[28] University of Pittsburgh,undefined

[29] St. Paul’s Hospital,undefined

[30] University of British Columbia,undefined

[31] University Medical Center Hamburg-Eppendorf,undefined

[32] University Medical Center Groningen,undefined

[33] University of Groningen,undefined

[34] AP-HP Université Paris-Saclay,undefined

[35] Inserm UMR S_999,undefined

[36] Ambroise Paré Hospital,undefined

[37] AP-HP,undefined

[38] Paris-Saclay University,undefined

[39] Erasme Univ Hospital,undefined

[40] Université Libre de Bruxelles,undefined

[41] HCor Research Institute,undefined

[42] D’Or Research and Education Institute,undefined

来源：

Intensive Care Medicine | 2022年 / 48卷

关键词：

Sepsis; Intensive care; Vasoactive drugs; Fluids; Fluid resuscitation; Treatment;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality. Even though large randomized, controlled trials have addressed fundamental aspects of septic shock resuscitation, many questions still exist. In this review, we will describe the current standards of septic shock resuscitation, but the emphasis will be placed on evolving concepts in different domains such as clinical resuscitation targets, adequate use of fluids and vasoactive drugs, refractory shock, and the use of extracorporeal therapies. Multiple research opportunities remain open, and collaborative endeavors should be performed to fill in these gaps.

引用

页码：148 / 163

页数：15

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