Regioselectivity of alkylation of 3-substituted 5-amino-1,2,4-thiadiazoles

被引：0
|
作者：
Khakimov M. [1 ]
Ambartsumova R.F. [1 ]
Tashkhodzhaev B. [1 ]
Antipin M.Yu. [2 ]
Shakhidoyatov Kh.M. [1 ]
机构：
[1] Acad. S. Yunusov Institute of Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
[2] A. N. Nesmeyanov Institute of Organoelement Compounds
来源：
Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 08期
关键词：
4-Alkyl-5-imino-4,5-dihydro-1,2,4-thiadiazoles; 5-Amino-1,2,4-thiadiazoles; Epichlorohydrin; Ethylene chlorohydrin; Tetrahydro-pyrimido[2,1-b]- 1,2,4-thiadiazoles; X-ray diffraction;
D O I：
10.1023/A:1012795819528
中图分类号：
学科分类号：
摘要：
We have synthesized 3-substituted 4-alkyl-5-imino-4,5-dihydro-1,2,4-thiadiazoles by reaction of 3-alkyl(benzyl)thio-5-amino-1,2,4-thiadiazoles with methyl iodide or ethylene chlorohydrin. In the reaction with epichlorohydrin, addition of an oxirane molecule occurs with formation of tetrahydropyrimido[2,1-b]-1,2,4-thiadiazoles.
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页码：1005 / 1010
页数：5
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