Regioselectivity of alkylation of 3-substituted 5-amino-1,2,4-thiadiazoles

被引：0

作者：

Khakimov M. ^{[1
]}

Ambartsumova R.F. ^{[1
]}

Tashkhodzhaev B. ^{[1
]}

Antipin M.Yu. ^{[2
]}

Shakhidoyatov Kh.M. ^{[1
]}

机构：

[1] Acad. S. Yunusov Institute of Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan

[2] A. N. Nesmeyanov Institute of Organoelement Compounds

来源：

Chemistry of Heterocyclic Compounds | 2001年 / 37卷 / 08期

关键词：

4-Alkyl-5-imino-4,5-dihydro-1,2,4-thiadiazoles; 5-Amino-1,2,4-thiadiazoles; Epichlorohydrin; Ethylene chlorohydrin; Tetrahydro-pyrimido[2,1-b]- 1,2,4-thiadiazoles; X-ray diffraction;

D O I：

10.1023/A:1012795819528

中图分类号：

学科分类号：

摘要：

We have synthesized 3-substituted 4-alkyl-5-imino-4,5-dihydro-1,2,4-thiadiazoles by reaction of 3-alkyl(benzyl)thio-5-amino-1,2,4-thiadiazoles with methyl iodide or ethylene chlorohydrin. In the reaction with epichlorohydrin, addition of an oxirane molecule occurs with formation of tetrahydropyrimido[2,1-b]-1,2,4-thiadiazoles.

引用

页码：1005 / 1010

页数：5

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