TRAFIC: statistical design and analysis plan for a pragmatic early phase 1/2 Bayesian adaptive dose escalation trial in rheumatoid arthritis

被引：0
|
作者：
M. Cole
C. Yap
C. Buckley
W. F. Ng
I. McInnes
A. Filer
S. Siebert
A. Pratt
J. D. Isaacs
D. D. Stocken
机构：
[1] Newcastle University,Population Health Sciences Institute
[2] The Institute of Cancer Research,Clinical Trials and Statistics Unit
[3] London,School of Immunity and Infection
[4] University of Birmingham,Translational and Clinical Research Institute
[5] Newcastle University,College of Medical, Veterinary and Life Sciences
[6] University of Glasgow,Leeds Institute of Clinical Trials Research
[7] University of Leeds,undefined
来源：
Trials | / 22卷
关键词：
CRM; Dose-finding; Adaptive; Early-phase; Clinical trial;
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