The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI

被引：0
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作者：
H. Bussey
R. K. Storms
A. Ahmed
K. Albermann
E. Allen
W. Ansorge
R. Araujo
A. Aparicio
B. Barrell
K. Badcock
V. Benes
D. Botstein
S. Bowman
M. Brückner
J. Carpenter
J. M. Cherry
E. Chung
C. Churcher
F. Coster
K. Davis
R. W. Davis
F. S. Dietrich
H. Delius
T. DiPaolo
E. Dubois
A. Düsterhöft
M. Duncan
M. Floeth
N. Fortin
J. D. Friesen
C. Fritz
A. Goffeau
J. Hall
U. Hebling
K. Heumann
H. Hilbert
L. Hillier
S. Hunicke-Smith
R. Hyman
M. Johnston
S. Kalman
K. Kleine
C. Komp
O. Kurdi
D. Lashkari
H. Lew
A. Lin
D. Lin
E. J. Louis
R. Marathe
机构：
[1] McGill University,Department of Biology
[2] Concordia University,Department of Biology
[3] Research Institute,Department of Biochemistry
[4] Hospital for Sick Children,The Genome Sequencing Center, Department of Genetics
[5] Martinsrieder Institut für Protein Sequenzen,Department Microbiologie
[6] Max-Planck-Institut für Biochemie,undefined
[7] Stanford University,undefined
[8] European Molecular Biology Laboratory,undefined
[9] The Sanger Centre,undefined
[10] Wellcome Trust Genome Campus,undefined
[11] Genotype GmbH,undefined
[12] Unité de Biochimie Physiologique,undefined
[13] Université Catholique de Louvain,undefined
[14] DKFZ,undefined
[15] Research Institute of CERIA-COOVI,undefined
[16] Laboratoire de Microbiologie de l’Université Libre de Bruxelles,undefined
[17] QIAGEN GmbH,undefined
[18] Washington University,undefined
[19] School of Medicine,undefined
[20] Yeast Genetics,undefined
[21] Institute of Molecular Medicine,undefined
[22] John Radcliffe Hospital,undefined
[23] Gesellschaft für Analyse Technik und Consulting mbH,undefined
[24] AGON,undefined
[25] Gesellschaft für molekularbiologische Technologie mbH,undefined
[26] Vlaams Interuniversitair Instituut voor Biothechnologie,undefined
[27] Laboratorium voor Erfelijkheidsleer en Microbiologie van de Vrije Universiteit,undefined
[28] Laboratoire de Physiologie Cellulaire et de Génétique des Levures,undefined
[29] Université Libre de Bruxelles,undefined
来源：
Nature | 1997年 / 387卷
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摘要：
The nucleotide sequence of the 948,061 base pairs of chromosome XVI has been determined, completing the sequence of the yeast genome. Chromosome XVI was the last yeast chromosome identified1, and some of the genes mapped early to it, such as GAL4, PEP4 and RAD1(ref. 2) have played important roles in the development of yeast biology. The architecture of this final chromosome seems to be typical of the large yeast chromosomes, and shows large duplications with other yeast chromosomes. Chromosome XVI contains 487 potential protein-encoding genes, 17 tRNA genes and two small nuclear RNA genes; 27% of the genes have significant similarities to human gene products, and 48% are new and of unknown biological function. Systematic efforts to explore gene function have begun.
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页码：103 / 105
页数：2
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