Epigenetic control of stem cell fate to neurons and glia

被引:0
|
作者
Hyun-Jung Kim
Michael G. Rosenfeld
机构
[1] Chung-Ang University,Laboratory of Molecular and Stem Cell Pharmacology, College of Pharmacy
[2] School of Medicine,Howard Hughes Medical Institute
[3] University of California,Department of Cellular and Molecular Medicine
[4] San Diego,undefined
[5] School of Medicine,undefined
来源
关键词
Histone modification; Non-coding RNA; Stem cell; Neuron; Glia;
D O I
暂无
中图分类号
学科分类号
摘要
How a cell fate is determined and how tremendously diverse cells are generated during development are interesting and intriguing questions to be solved before using the stem cells for therapeutic purpose. Recently, it has been suggested that epigenetic control by the histone modifying enzymes and non-coding RNAs play important roles in guiding stem cells to differentiate into neurons or glia. In this review, we discuss the recent outcomes and advances in understanding the histone modifying enzymes and non-coding RNAs during neural cell-type specification of stem cells.
引用
收藏
页码:1467 / 1473
页数:6
相关论文
共 50 条
  • [21] Epigenetic programming defines haematopoietic stem cell fate restriction
    Yiran Meng
    Joana Carrelha
    Roy Drissen
    Xiying Ren
    Bowen Zhang
    Adriana Gambardella
    Simona Valletta
    Supat Thongjuea
    Sten Eirik Jacobsen
    Claus Nerlov
    Nature Cell Biology, 2023, 25 : 812 - 822
  • [22] Matrix control of stem cell fate
    Even-Ram, Sharona
    Artym, Vira
    Yamada, Kenneth M.
    CELL, 2006, 126 (04) : 645 - 647
  • [23] Intrinsic control of stem cell fate
    Lansdorp, PM
    STEM CELLS, 1997, 15 : 223 - 225
  • [24] The "nuclear physics" behind epigenetic control of cell fate
    Zijl, Sebastiaan
    Lomakin, Alexis J.
    EXPERIMENTAL CELL RESEARCH, 2019, 376 (02) : 236 - 239
  • [25] Neural stem cells, neurons, and glia
    Pollard, Steven M.
    Benchoua, Alex
    Lowell, Sally
    EMBRYONIC STEM CELLS, 2006, 418 : 151 - 169
  • [26] EPIGENETIC MECHANISMS UNDERLIE NANOTOPOGRAPHICAL REGULATION OF SKELETAL STEM CELL FATE
    Kingham, Emmajayne
    Gadegaard, Nikolaj
    Dalby, Matthew
    Oreffo, Richard
    OSTEOPOROSIS INTERNATIONAL, 2012, 23 : S591 - S592
  • [27] Epigenetic plasticity and redox regulation of neural stem cell state and fate
    Tay, Emmy Xue Yun
    Chia, Kimberly
    Ong, Derrick Sek Tong
    FREE RADICAL BIOLOGY AND MEDICINE, 2021, 170 : 116 - 130
  • [28] JMJD3: a critical epigenetic regulator in stem cell fate
    Ding, Yuanjie
    Yao, Yuanchun
    Gong, Xingmu
    Zhuo, Qi
    Chen, Jinhua
    Tian, Miao
    Farzaneh, Maryam
    CELL COMMUNICATION AND SIGNALING, 2021, 19 (01)
  • [29] JMJD3: a critical epigenetic regulator in stem cell fate
    Yuanjie Ding
    Yuanchun Yao
    Xingmu Gong
    Qi Zhuo
    Jinhua Chen
    Miao Tian
    Maryam Farzaneh
    Cell Communication and Signaling, 19
  • [30] Epigenetic control of adult stem cell function
    Alexandra Avgustinova
    Salvador Aznar Benitah
    Nature Reviews Molecular Cell Biology, 2016, 17 : 643 - 658