Mechanisms of Disease: signal transduction in lung carcinogenesis—a comparison of smokers and never-smokers

被引：0

作者：

Giannis Mountzios

Pierre Fouret

Jean-Charles Soria

机构：

[1] Athens,G Mountzios is a Medical Oncologist in the Department of Clinical Therapeutics at the University Hospital Alexandra

[2] Greece,P Fouret is Professor of Pathology and Head of the Laboratory of Translational Research and J

[3] both at Université Paris XI,C Soria is Professor of Medicine and Medical Oncology in the Department of Medicine

[4] Institut Gustave Roussy,undefined

[5] Paris,undefined

[6] France.,undefined

来源：

Nature Clinical Practice Oncology | 2008年 / 5卷

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D O I：

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学科分类号：

摘要：

Our understanding of the pathogenesis of tobacco-related lung carcinogenesis is improving but the molecular mechanisms of neoplastic transformation in never-smokers have not yet been elucidated. Mountzios et al. describe the best characterized signaling pathways that are implicated in the transduction of proliferative signals, and discuss the differences in the molecular characteristics of smokers and never-smokers.

引用

页码：610 / 618

页数：8

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