Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

被引：0

作者：

Roksana M Pirzgalska

Elsa Seixas

Jason S Seidman

Verena M Link

Noelia Martínez Sánchez

Inês Mahú

Raquel Mendes

Vitka Gres

Nadiya Kubasova

Imogen Morris

Bernardo A Arús

Chelsea M Larabee

Miguel Vasques

Francisco Tortosa

Ana L Sousa

Sathyavathy Anandan

Erin Tranfield

Maureen K Hahn

Matteo Iannacone

Nathanael J Spann

Christopher K Glass

Ana I Domingos

机构：

[1] The Howard Hughes Medical Institute (HHMI) and Obesity Laboratory,Department of Cellular and Molecular Medicine

[2] Instituto Gulbenkian de Ciência,Department II

[3] University of California,Departamento de Bioquímica

[4] Faculty of Biology,Department of Endocrinology

[5] Ludwig-Maximilians Universität München,Department of Pathology

[6] Instituto de Ciências Básicas da Saúde,Division of Immunology

[7] Universidade Federal do Rio Grande do Sul,undefined

[8] Curry Cabral Hospital,undefined

[9] Centro Hospitalar de Lisboa Central,undefined

[10] Centro Hospitalar Lisboa Norte,undefined

[11] Hospital de Santa Maria,undefined

[12] EPE,undefined

[13] Electron Microscopy Unit,undefined

[14] Instituto Gulbenkian de Ciência,undefined

[15] Vanderbilt Kennedy Center for Research on Human Development,undefined

[16] Vanderbilt University School of Medicine,undefined

[17] Transplantation and Infectious Diseases,undefined

[18] Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute,undefined

[19] The Howard Hughes Medical Institute (HHMI),undefined

[20] New York,undefined

来源：

Nature Medicine | 2017年 / 23卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Sympathetic neuron–associated macrophages act as a local sink for norepinephrine, leading to reduced thermogenesis and increased obesity.

引用

页码：1309 / 1318

页数：9

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