Sympathetic neuron–associated macrophages contribute to obesity by importing and metabolizing norepinephrine

被引：0

作者：

Roksana M Pirzgalska

Elsa Seixas

Jason S Seidman

Verena M Link

Noelia Martínez Sánchez

Inês Mahú

Raquel Mendes

Vitka Gres

Nadiya Kubasova

Imogen Morris

Bernardo A Arús

Chelsea M Larabee

Miguel Vasques

Francisco Tortosa

Ana L Sousa

Sathyavathy Anandan

Erin Tranfield

Maureen K Hahn

Matteo Iannacone

Nathanael J Spann

Christopher K Glass

Ana I Domingos

机构：

[1] The Howard Hughes Medical Institute (HHMI) and Obesity Laboratory,Department of Cellular and Molecular Medicine

[2] Instituto Gulbenkian de Ciência,Department II

[3] University of California,Departamento de Bioquímica

[4] Faculty of Biology,Department of Endocrinology

[5] Ludwig-Maximilians Universität München,Department of Pathology

[6] Instituto de Ciências Básicas da Saúde,Division of Immunology

[7] Universidade Federal do Rio Grande do Sul,undefined

[8] Curry Cabral Hospital,undefined

[9] Centro Hospitalar de Lisboa Central,undefined

[10] Centro Hospitalar Lisboa Norte,undefined

[11] Hospital de Santa Maria,undefined

[12] EPE,undefined

[13] Electron Microscopy Unit,undefined

[14] Instituto Gulbenkian de Ciência,undefined

[15] Vanderbilt Kennedy Center for Research on Human Development,undefined

[16] Vanderbilt University School of Medicine,undefined

[17] Transplantation and Infectious Diseases,undefined

[18] Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute,undefined

[19] The Howard Hughes Medical Institute (HHMI),undefined

[20] New York,undefined

来源：

Nature Medicine | 2017年 / 23卷

关键词：

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学科分类号：

摘要：

Sympathetic neuron–associated macrophages act as a local sink for norepinephrine, leading to reduced thermogenesis and increased obesity.

引用

页码：1309 / 1318

页数：9

共 50 条

[1] Sympathetic neuron-associated macrophages contribute to obesity by importing and metabolizing norepinephrine
Pirzgalska, Roksana M.
Seixas, Elsa
Seidman, Jason S.
Link, Verena M.
Sanchez, Noelia Martinez
Mahu, Ines
Mendes, Raquel
Gres, Vitka
Kubasova, Nadiya
Morris, Imogen
Arus, Bernardo A.
Larabee, Chelsea M.
Vasques, Miguel
Tortosa, Francisco
Sousa, Ana L.
Anandan, Sathyavathy
Tranfield, Erin
Hahn, Maureen K.
Iannacone, Matteo
Spann, Nathanael J.
Glass, Christopher K.
Domingos, Ana I.
NATURE MEDICINE, 2017, 23 (11) : 1309 - +
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