Classification and biological identity of complex nano shapes

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作者
Luca Boselli
Hender Lopez
Wei Zhang
Qi Cai
Valeria A. Giannone
Jingji Li
Alirio Moura
João M. de Araujo
Jennifer Cookman
Valentina Castagnola
Yan Yan
Kenneth A. Dawson
机构
[1] University College Dublin,Centre for BioNano Interactions, School of Chemistry
[2] Technological University Dublin,School of Physics and Optometric & Clinical Sciences
[3] Guangzhou Medical University,Guangdong Provincial Education Department Key Laboratory of Nano
[4] Guangzhou,Immunoregulation Tumor Microenvironment The Second Affiliated Hospital
[5] Departamento de Física Teórica e Experimental,School of Biomolecular and Biomedical Science
[6] Universidade Federal do Rio Grande do Norte,undefined
[7] University College Dublin,undefined
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摘要
Everywhere in our surroundings we increasingly come in contact with nanostructures that have distinctive complex shape features on a scale comparable to the particle itself. Such shape ensembles can be made by modern nano-synthetic methods and many industrial processes. With the ever growing universe of nanoscale shapes, names such as “nanoflowers” and “nanostars” no longer precisely describe or characterise the distinct nature of the particles. Here we capture and digitise particle shape information on the relevant size scale and create a condensed representation in which the essential shape features can be captured, recognized and correlated. We find the natural emergence of intrinsic shape groups as well-defined ensemble distributions and show how these may be analyzed and interpreted to reveal novel aspects of our nanoscale shape environment. We show how these ideas may be applied to the interaction between the nanoscale-shape and the living universe and provide a conceptual framework for the study of nanoscale shape biological recognition and identity.
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