Open questions: CRISPR biology

被引:0
|
作者
Eugene V. Koonin
机构
[1] National Center for Biotechnology Information,
[2] National Library of Medicine,undefined
来源
BMC Biology | / 16卷
关键词
Genome Engineering Tools; Archaea; Altruistic Suicide; CRISPR-mediated Immunity; Endogenous Gene Regulation;
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暂无
中图分类号
学科分类号
摘要
CRISPR-Cas systems, the purveyors of adaptive immunity in archaea and bacteria and sources of the new generation of genome engineering tools, have been studied in exquisite molecular detail. However, when it comes to biological functions, ecology, and evolution of CRISPR-Cas, many more intriguing questions remain than there are answers.
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