COVID-19;
Pandemic model;
Hierarchical quarantine;
Time delay;
Bifurcation;
D O I:
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摘要:
COVID-19 comes out as a sudden pandemic disease within human population. The pandemic dynamics of COVID-19 needs to be studied in detail. A pandemic model with hierarchical quarantine and time delay is proposed in this paper. In the COVID-19 case, the virus incubation period and the antibody failure will cause the time delay and reinfection, respectively, and the hierarchical quarantine strategy includes home isolation and quarantine in hospital. These factors that affect the spread of COVID-19 are well considered and analyzed in the model. The stability of the equilibrium and the nonlinear dynamics is studied as well. The threshold value τk\documentclass[12pt]{minimal}
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\begin{document}$$\tau_{k}$$\end{document} of the bifurcation is deduced and quantitatively analyzed. Numerical simulations are performed to establish the analytical results with suitable examples. The research reveals that the COVID-19 outbreak may recur over a period of time, which can be helpful to increase the number of tested people with or without symptoms in order to be able to early identify the clusters of infection. And before the effective vaccine is successfully developed, the hierarchical quarantine strategy is currently the best way to prevent the spread of this pandemic.
机构:
Univ Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, ItalyUniv Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, Italy
Pinchi, Vilma
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Brambilla, Eugenio
Cairo, Francesco
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Univ Firenze, Dipartimento Med Sperimentale & Clin, Unita Ric Parodontol & Med Parodontale, Florence, ItalyUniv Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, Italy
Cairo, Francesco
Norelli, Gian-Aristide
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Univ Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, ItalyUniv Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, Italy
Norelli, Gian-Aristide
Iavicoli, Ivo
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Univ Napoli Federico II, Dipartimento San Pubbl, Sez Med Lavoro, Naples, ItalyUniv Firenze, Dipartimento Sci Salute, Sez Sci Med Forensi, Florence, Italy
机构:
Univ Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, ItalyUniv Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
Villa, Simone
Jaramillo, Ernesto
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World Hlth Org, Global TB Programme, Geneva, SwitzerlandUniv Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
Jaramillo, Ernesto
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Mangioni, Davide
Bandera, Alessandra
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Univ Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
IRCCS Ca Granda Osped Maggiore Policlin Fdn, Infect Dis Unit, Milan, ItalyUniv Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
Bandera, Alessandra
Gori, Andrea
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Univ Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
IRCCS Ca Granda Osped Maggiore Policlin Fdn, Infect Dis Unit, Milan, ItalyUniv Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
Gori, Andrea
Raviglione, Mario Carlo
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Univ Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, ItalyUniv Milan, Ctr Multidisciplinary Res Hlth Sci, Via Francesco Sforza 35, I-20122 Milan, Italy
机构:
Univ Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USAUniv Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USA
Phillips, Heather
Deshpandey, Manasi
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Univ Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USAUniv Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USA
Deshpandey, Manasi
Staveski, Sandra
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Univ Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USA
Univ Calif San Francisco, 2 Koret Way, San Francisco, CA 94143 USAUniv Calif San Francisco, Sch Nursing, Dept Family Hlth Care Nursing, San Francisco, CA USA
Staveski, Sandra
JOURNAL OF PEDIATRIC NURSING-NURSING CARE OF CHILDREN & FAMILIES,
2024,
74
: 129
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131
机构:
UKE Kore Univ Enna, Fac Human & Social Sci, Enna, ItalyUniv Sydney, Fac Med & Hlth, Sydney Med Sch, Nepean Clin Sch,Discipline Psychiat, Sydney, NSW, Australia
Schimmenti, Adriano
Billieux, Joel
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Univ Lausanne, Inst Psychol, Lausanne, SwitzerlandUniv Sydney, Fac Med & Hlth, Sydney Med Sch, Nepean Clin Sch,Discipline Psychiat, Sydney, NSW, Australia
Billieux, Joel
Berle, David
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机构:
Univ Technol Sydney, Grad Sch Hlth, Discipline Clin Psychol, Ultimo, NSW, Australia
Univ New South Wales, Sch Psychiat, Sydney, NSW, AustraliaUniv Sydney, Fac Med & Hlth, Sydney Med Sch, Nepean Clin Sch,Discipline Psychiat, Sydney, NSW, Australia
机构:
Jawaharlal Nehru Univ, Sch Social Sci, Ctr Study Reg Dev, New Delhi 110067, IndiaJawaharlal Nehru Univ, Sch Social Sci, Ctr Study Reg Dev, New Delhi 110067, India
Mondal, Sandip
Karmakar, Ranjan
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Jawaharlal Nehru Univ, Sch Social Sci, Ctr Study Reg Dev, New Delhi 110067, IndiaJawaharlal Nehru Univ, Sch Social Sci, Ctr Study Reg Dev, New Delhi 110067, India