Randomized controlled double-blind trial of methylprednisolone versus placebo in patients with post-COVID-19 syndrome and cognitive deficits: study protocol of the post-corona-virus immune treatment (PoCoVIT) trial

被引:0
|
作者
Christiana Franke
Vanessa Raeder
Fabian Boesl
Benno Bremer
Lucas C. Adam
Ameli Gerhard
Irina Eckert
Anneke Quitschau
Anne Pohrt
Susen Burock
Lisa Bruckert
Carmen Scheibenbogen
Harald Prüß
Heinrich J. Audebert
机构
[1] Charité – Universitätsmedizin Berlin,Department of Neurology and Experimental Neurology, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin
[2] Charité Campus Benjamin Franklin,Corporate Member of Freie Universität Berlin and Humboldt
[3] Charité - Universitätsmedizin Berlin,Universität zu Berlin, Institute of Biometry and Clinical Epidemiology
[4] Charité - Universitätsmedizin Berlin,Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Clinical Trial Office
[5] Charité - Universitätsmedizin Berlin,Department of Neurology, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin
[6] Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE),Institute of Medical Immunology, Corporate Member of Freie Universität Berlin and Humboldt
[7] Charité – Universitätsmedizin Berlin,Universität zu Berlin
关键词
Post-COVID; Long-COVID; Glucocorticoids; Treatment; Methylprednisolone; Placebo-controlled trial protocol; Pathophysiology;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Effects of Pycnogenol® in people with post-COVID-19 condition (PYCNOVID): study protocol for a single-center, placebo controlled, quadruple-blind, randomized trial
    Radtke, Thomas
    Kunzi, Lisa
    Kopp, Julia
    Rasi, Manuela
    Braun, Julia
    Zens, Kyra D.
    Winter, Babette
    Anagnostopoulos, Alexia
    Puhan, Milo A.
    Fehr, Jan S.
    TRIALS, 2024, 25 (01)
  • [22] A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial
    Karen M Barlow
    Brian L Brooks
    Frank P MacMaster
    Adam Kirton
    Trevor Seeger
    Michael Esser
    Susan Crawford
    Alberto Nettel-Aguirre
    Roger Zemek
    Mikrogianakis Angelo
    Valerie Kirk
    Carolyn A Emery
    David Johnson
    Michael D Hill
    Jeff Buchhalter
    Brenda Turley
    Lawrence Richer
    Robert Platt
    Jamie Hutchison
    Deborah Dewey
    Trials, 15
  • [23] A double-blind, placebo-controlled intervention trial of 3 and 10 mg sublingual melatonin for post-concussion syndrome in youths (PLAYGAME): study protocol for a randomized controlled trial
    Barlow, Karen M.
    Brooks, Brian L.
    MacMaster, Frank P.
    Kirton, Adam
    Seeger, Trevor
    Esser, Michael
    Crawford, Susan
    Nettel-Aguirre, Alberto
    Zemek, Roger
    Angelo, Mikrogianakis
    Kirk, Valerie
    Emery, Carolyn A.
    Johnson, David
    Hill, Michael D.
    Buchhalter, Jeff
    Turley, Brenda
    Richer, Lawrence
    Platt, Robert
    Hutchison, Jamie
    Dewey, Deborah
    TRIALS, 2014, 15
  • [24] Plasma exchange therapy for the post COVID-19 condition: a phase II, double-blind, placebo-controlled, randomized trial
    Espana-Cueto, Sergio
    Loste, Cora
    Llados, Gemma
    Lopez, Cristina
    Santos, Jose Ramon
    Dulsat, Gemma
    Garcia, Anna
    Carmezim, Joao
    Carabia, Julia
    Ancochea, Agueda
    Fernandez-Prendres, Carla
    Morales-Indiano, Cristian
    Quirant, Bibiana
    Martinez-Caceres, Eva
    Sanchez, Anna
    Parraga, Ivonne Graciela
    Chamorro, Anna
    San Jose, Alba
    Abad, Elena
    Munoz-Moreno, Jose A.
    Prats, Anna
    Fumaz, Carmina R.
    Coll-Fernandez, Roser
    Estany, Carla
    Torrano, Pamela
    Puig, Jordi
    Clotet, Bonaventura
    Tebe, Cristian
    Massanella, Marta
    Paredes, Roger
    Mateu, Lourdes
    NATURE COMMUNICATIONS, 2025, 16 (01)
  • [25] A randomized double-blind controlled trial of sulphasalazine combined with pulses of methylprednisolone or placebo in the treatment of rheumatoid arthritis
    Ciconelli, RM
    Ferraz, MB
    Visioni, RA
    Oliveira, LM
    Atra, E
    BRITISH JOURNAL OF RHEUMATOLOGY, 1996, 35 (02): : 150 - 154
  • [26] Metoclopramide for the treatment of Tourette syndrome: A randomized, double-blind, placebo-controlled trial
    Nicolson, R
    Smith, J
    Castellanos, FX
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2004, 7 : S277 - S277
  • [27] Vasopressin and methylprednisolone for in-hospital cardiac arrest - Protocol for a randomized, double-blind, placebo-controlled trial
    Andersen, Lars W.
    Sindberg, Birthe
    Holmberg, Mathias
    Isbye, Dan
    Kjaergaard, Jesper
    Zwisler, Stine T.
    Darling, Soren
    Larsen, Jacob Moesgaard
    Rasmussen, Bodil S.
    Lofgren, Bo
    Lauridsen, Kasper Glerup
    Paelestik, Kim B.
    Solling, Christoffer
    Kjaergaard, Anders G.
    Due-Rasmussen, Dorte
    Folke, Fredrik
    Charlot, Mette Gitz
    Iversen, Kasper
    Schultz, Martin
    Wiberg, Sebastian
    Jepsen, Rikke Malene H. G.
    Kurth, Tobias
    Donnino, Michael
    Kirkegaard, Hans
    Granfeldt, Asger
    RESUSCITATION PLUS, 2021, 5
  • [28] Milnacipran for the treatment of fibromyalgia syndrome: A randomized, double-blind, placebo-controlled trial
    Clauw, Daniel J.
    Palmer, Robert H.
    Thacker, Kim
    Gendreau, R. Michael
    Mease, Philip
    NEUROLOGY, 2008, 70 (11) : A162 - A162
  • [29] Comment on: "Intravenous methylprednisolone pulses in hospitalized patients with severe COVID-19 pneumonia: a double-blind, randomized, placebo-controlled trial"
    Patrucco, Filippo
    Gavelli, Filippo Francesco
    Fantin, Alberto
    Solidoro, Paolo
    GAZZETTA MEDICA ITALIANA ARCHIVIO PER LE SCIENZE MEDICHE, 2022, 181 (12) : 1003 - 1004
  • [30] Tramadol in post-herpetic neuralgia: a randomized, double-blind, placebo-controlled trial
    Boureau, F
    Legallicier, P
    Kabir-Ahmadi, M
    PAIN, 2003, 104 (1-2) : 323 - 331