Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation

被引:0
|
作者
Nathalia R. V. Dragano
Carina Solon
Albina F. Ramalho
Rodrigo F. de Moura
Daniela S. Razolli
Elisabeth Christiansen
Carlos Azevedo
Trond Ulven
Licio A. Velloso
机构
[1] University of Campinas,Laboratory of Cell Signaling and Obesity and Comorbidities Research Center
[2] University of Southern Denmark,Department of Physics, Chemistry and Pharmacy
[3] University of Campinas,Laboratory of Cell Signaling
关键词
GPR40; GPR120; Obesity; Hypothalamic inflammation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Regulation of the gene encoding GPR40, a fatty acid receptor expressed selectively in pancreatic β cells
    Bartoov-Shifman, Reut
    Ridner, Gabriela
    Bahar, Keren
    Rubins, Nir
    Walker, Michael D.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (32) : 23561 - 23571
  • [32] Physiology and Therapeutics of the Free Fatty Acid Receptor GPR40
    Huang, Hui
    Dai, Meng-Hong
    Tao, Ya-Xiong
    GLUCOSE HOMEOSTATIS AND THE PATHOGENESIS OF DIABETES MELLITUS, 2014, 121 : 67 - 94
  • [33] Role of free fatty acid receptor GPR120 in metabolic regulation
    Hirasawa, Akira
    Hara, Takafumi
    Ichimura, Atsuhiko
    Miyauchi, Satoshi
    Kimura, Ikuo
    Taka-aki, Koshimizu
    Tsujimoto, Gozoh
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2010, 112 : 20P - 20P
  • [34] Gpr40 is expressed in enteroendocrine cells and mediates free fatty acid stimulation of incretin secretion
    Edfalk, Sara
    Steneberg, Par
    Edlund, Helena
    DIABETES, 2008, 57 (09) : 2280 - 2287
  • [35] Fatty acid receptor GPR120: a novel marker for human melanoma
    Kleemann, Johannes
    Hrgovic, Igor
    Ter-Nedden, Jan
    Kleimann, Pia
    Steinhorst, Katja
    Haerle, Katja
    Mueller, Jutta
    Kaufmann, Roland
    Meissner, Markus
    Kippenberger, Stefan
    MELANOMA RESEARCH, 2018, 28 (04) : 271 - 276
  • [36] Unsaturated fatty acids from flaxseed oil and exercise modulate GPR120 but not GPR40 in the liver of obese mice: a new anti-inflammatory approach
    Gaspar, Rafael Calais
    Veiga, Camilla Bertuzzo
    Bessi, Mariana Pereira
    Datilo, Marcella Neves
    Sant'Ana, Marcella Ramos
    Rodrigues, Patricia Brito
    de Moura, Leandro Pereira
    Ramos da Silva, Adelino Sanchez
    Santos, Gustavo Aparecido
    Catharino, Rodrigo Ramos
    Ropelle, Eduardo Rochete
    Pauli, Jose Rodrigo
    Cintra, Dennys Esper
    JOURNAL OF NUTRITIONAL BIOCHEMISTRY, 2019, 66 : 52 - 62
  • [38] GPR120和GPR40表达与卵巢癌临床病理特征及预后的关系
    李娟
    倪惠华
    天津医药, 2023, 51 (05) : 522 - 526
  • [39] Different effects of GPR120 and GPR40 on cellular functions stimulated by 12-O-tetradecanoylphorbol-13-acetate in melanoma cells
    Fukushima, Kaori
    Takahashi, Kaede
    Fukushima, Nobuyuki
    Honoki, Kanya
    Tsujiuchi, Toshifumi
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2016, 475 (01) : 25 - 30
  • [40] Cloning, expression, and pharmacological characterization of the GPR120 free fatty acid receptor from cynomolgus monkey: Comparison with human GPR120 splice variants
    Moore, Kristina
    Zhang, Qing
    Murgolo, Nick
    Hosted, Tom
    Duffy, Ruth
    COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2009, 154 (04): : 419 - 426