The origin of the large metacentric chromosome pair in Chinese medaka (Oryzias sinensis)

被引:0
|
作者
Taijun Myosho
Yusuke Takehana
Tadashi Sato
Satoshi Hamaguchi
Mitsuru Sakaizumi
机构
[1] Niigata University,Institute of Science and Technology
[2] National Institute for Basic Biology,Laboratory of Bioresources
来源
Ichthyological Research | 2012年 / 59卷
关键词
Chinese medaka; Robertsonian fusion; FISH; Linkage analysis;
D O I
暂无
中图分类号
学科分类号
摘要
Japanese medakas (Oryzias latipes and Oryzias sakaizumii) have 48 chromosomes, while the Chinese medaka (Oryzias sinensis) has 46 chromosomes, including one pair of large metacentric chromosomes. Linkage analysis using O. sakaizumii and O. sinensis strains showed that DNA markers in linkage groups (LG) 11 and 13 were tightly linked. Centromeric genomic clones of LG 11 and 13 derived from an O. latipes strain hybridized across the centromeres of the pair of large metacentric chromosomes in an O. sinensis strain. These results demonstrate that the large metacentric chromosome pair was derived from two pairs of acrocentric chromosomes (LG 11 and 13) through Robertsonian fusion.
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页码:384 / 388
页数:4
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