Long non-coding RNAs in cardiac hypertrophy

被引:0
|
作者
Jinghui Sun
Chenglong Wang
机构
[1] Cardiovascular Disease Research Center,
[2] Xiyuan Hospital,undefined
[3] China Academy of Chinese Medical Sciences,undefined
来源
Heart Failure Reviews | 2020年 / 25卷
关键词
Cardiac hypertrophy; Long non-coding RNAs; Heart failure; Cardiac remodeling;
D O I
暂无
中图分类号
学科分类号
摘要
Cardiac hypertrophy (CH) is generally considered adaptive responses that may occur after myocardial infarction, pressure overload, volume overload, inflammatory heart muscle disease, or idiopathic dilated cardiomyopathy, whereas long-term stimulation eventually leads to heart failure (HF). However, the current molecular mechanisms involved in CH are unclear. Recently, increasing evidences reveal that long non-coding RNAs (lncRNAs) play vital roles in CH. Different lncRNAs can promote or inhibit the pathological process of CH by different mechanisms, while the regulation of lncRNAs expression can improve CH. Thus, CH-related lncRNAs may become a novel field of research on CH.
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页码:1037 / 1045
页数:8
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