Time-level relationship for nitric oxide and the protective effects of aminoguanidine in experimental spinal cord injury

被引:0
|
作者
O. Soy
Ö Aslan
H. Uzun
Ş. Barut
A. Akyildiz İğdem
A. Belce
A. Çolak
机构
[1] Taksim Education and Research Hospital,Department of Neurosurgery
[2] Taksim Education and Research Hospital,Department of Pathology
[3] Istanbul University,Departments of Biochemistry
[4] Cerrrahpaşa School of Medicine,undefined
来源
Acta Neurochirurgica | 2004年 / 146卷
关键词
Keywords: Aminoguanidine; lipid peroxidation; neuroprotection; nitric oxide; nitric oxide synthase; spinal cord injury.;
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学科分类号
摘要
Background. The secondary injury process following spinal cord trauma has been shown to involve different mechanisms such as excessive release of excitatory amino-acids, and induction of free radical induced lipid peroxidation. In this experimental study, the time-level relationship of the nitric oxide and the neuroprotective effects of aminoguanidine were investigated in a rat spinal cord trauma model.
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页码:1329 / 1336
页数:7
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