3D modelling and simulation of the impact of wearing a mask on the dispersion of particles carrying the SARS-CoV-2 virus in a railway transport coach

被引:0
|
作者
Patrick Armand
Jérémie Tâche
机构
[1] CEA,
[2] DAM,undefined
[3] DIF,undefined
[4] FLUIDIAN,undefined
来源
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Even though the Covid-19 pandemic seems to be stagnating or decreasing across the world, a resurgence of the disease or the occurrence of other epidemics caused by the aerial dissemination of pathogenic biological agents cannot be ruled out. These agents, in particular the virions of the Covid-19 disease, are found in the particles originating from the sputum of infected symptomatic or asymptomatic people. In previous research, we made use of a three-dimensional Computational Fluid Dynamics (CFD) model to simulate particle transport and dispersion in ventilated semi-confined spaces. By way of illustration, we considered a commuter train coach in which an infected passenger emitted droplets (1 and 10 µm) and drops (100 and 1000 µm) while breathing and coughing. Using an Eulerian approach and a Lagrangian approach, we modelled the dispersion of the particles in the turbulent flow generated by the ventilation of the coach. The simulations returned similar results from both approaches and clearly demonstrated the very distinct aerodynamics of the aerosol of airborne droplets and, at the other end of the spectrum, of drops falling or behaving like projectiles depending on their initial velocity. That numerical study considered passengers without protective masks. In this new phase of research, we first used literature data to develop a model of a typical surgical mask for use on a digital manikin representing a human. Next, we resumed the twin experiment of the railway coach, but this time, the passengers (including the infected one) were provided with surgical masks. We compared the spatial and temporal distributions of the particles depending on whether the spreader passenger wore a mask at all, and whether the mask was perfectly fitted (without leaks) or worn loosely (with leaks). Beyond demonstrating the obvious value of wearing a mask in limiting the dissemination of particles, our model and our simulations allow a quantification of the ratio of particles suspended in the coach depending on whether the infected passenger wears a mask or not. Moreover, the calculations carried out constitute only one illustrative application among many others, not only in public transport, but in any other public or private ventilated space on the basis of the same physical models and digital twins of the places considered. CFD therefore makes it possible to estimate the criticality of the occupation of places by people with or without a mask and to recommend measures in order to limit aerial contamination by any kind of airborne pathogen, such as the virions of Covid-19.
引用
收藏
相关论文
共 50 条
  • [41] Production of a thermoplastic polyurethane/silver nanoparticles 3D filament with antiviral properties to combat SARS-CoV-2
    Agnol, Lucas Dall
    Ornaghi Jr, Heitor Luiz
    Ernzen, Juliano Roberto
    Faccio, Maira
    Bianchi, Otavio
    POLYMER ENGINEERING AND SCIENCE, 2024, 64 (01): : 130 - 141
  • [42] 3D culture models to study SARS-CoV-2 infectivity and antiviral candidates: From spheroids to bioprinting
    de Melo, Bruna A. G.
    Benincasa, Julia C.
    Cruz, Elisa M.
    Maricato, Juliana Terzi
    Porcionatto, Marimelia A.
    BIOMEDICAL JOURNAL, 2021, 44 (01) : 31 - 42
  • [43] Condensed Liquid Phase 3D Structure of SARS-CoV-2 s2m Guided by NMR Spectroscopy
    Pellegrene, Kendy A.
    Imperatore, Joshua A.
    Cunningham, Caylee L.
    Kensinger, Adam H.
    Mihailescu, Petru
    Srnec, Matthew N.
    Mihailescu, Mihaela-Rita
    Evanseck, Jeffrey D.
    BIOPHYSICAL JOURNAL, 2021, 120 (03) : 313A - 313A
  • [44] Harnessing 2D and 3D human endometrial cell culture models to investigate SARS-CoV-2 infection in early pregnancy
    Liu, Anna
    Ruetalo, Natalia
    Xavier, Janet P. Raja
    Lankapalli, Aditya Kumar
    Admard, Jakob
    Camarena-Sainz, Miguel
    Brucker, Sara Y.
    Singh, Yogesh
    Schindler, Michael
    Salker, Madhuri S.
    CLINICAL SCIENCE, 2025, 139 (04) : 1 - 21
  • [45] Multiplexed colorimetric detection of SARS-CoV-2 and other pathogens in wastewater on a 3D printed integrated microfluidic chip
    Yin, Kun
    Ding, Xiong
    Xu, Zhiheng
    Li, Ziyue
    Wang, Xingyu
    Zhao, Hui
    Otis, Clifford
    Li, Baikun
    Liu, Changchun
    SENSORS AND ACTUATORS B-CHEMICAL, 2021, 344
  • [46] De novo 3D models of SARS-CoV-2 RNA elements from consensus experimental secondary structures
    Rangan, Ramya
    Watkins, Andrew M.
    Chacon, Jose
    Kretsch, Rachael
    Kladwang, Wipapat
    Zheludev, Ivan N.
    Townley, Jill
    Rynge, Mats
    Thain, Gregory
    Das, Rhiju
    NUCLEIC ACIDS RESEARCH, 2021, 49 (06) : 3092 - 3108
  • [47] Level up for culture models - How 3D cell culture models benefit SARS-CoV-2 research
    Hafner, Sophia Julia
    BIOMEDICAL JOURNAL, 2021, 44 (01) : 1 - 6
  • [48] Cost-effective 3D lung tissue spheroid as a model for SARS-CoV-2 infection and drug screening
    Miranda, Guilherme A. S. C.
    Correa, Isadora Alonso
    Amorim, Erica Almeida
    Caldas, Lucio Ayres
    Carneiro, Fabiana Avila
    da Costa, Luciana Jesus
    Granjeiro, Jose Mauro
    Tanuri, Amilcar
    de Souza, Wanderley
    Baptista, Leandra Santos
    ARTIFICIAL ORGANS, 2024, 48 (07) : 723 - 733
  • [49] Design and Modelling of Surface Plasmon Resonance Biosensor Employing BaTiO3 and Graphene Nanostructure for Detection of SARS-CoV-2 Virus
    Alaaudeen, K. M.
    Manoharadas, Salim
    Dhasarathan, Vigneswaran
    Rajeshkannan, S.
    PLASMONICS, 2024, 20 (2) : 709 - 719
  • [50] Transferability Limitations for Covid 3D Localization Using SARS-CoV-2 Segmentation Models in 4D CT Images
    Maganaris, Constantine
    Protopapadakis, Eftychios
    Bakalos, Nikolaos
    Doulamis, Nikolaos
    Kalogeras, Dimitris
    Angeli, Aikaterini
    ADVANCES IN VISUAL COMPUTING, ISVC 2022, PT II, 2022, 13599 : 320 - 331