Ablation of phospholamban reverses slowed relaxation but not cardiac hypertrophy in mice lacking SERCA2a

被引：0
|
作者：
Louch, WE
Vangheluwe, P
Tjwa, M
Van Heyen, M
Kranias, E
Wuytack, F
Sipido, K
机构：
[1] Catholic Univ Louvain, B-3000 Louvain, Belgium
[2] Univ Cincinnati, Cincinnati, OH 45267 USA
来源：
BIOPHYSICAL JOURNAL | 2003年 / 84卷 / 02期
关键词：
D O I：
暂无
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：98A / 98A
页数：1
相关论文
共 50 条
  • [31] Resveratrol protects against lipopolysaccharide-induced cardiac dysfunction by enhancing SERCA2a activity through promoting the phospholamban oligomerization
    Bai, Tao
    Hu, Xinyue
    Zheng, Yang
    Wang, Shudong
    Kong, Jian
    Cai, Lu
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2016, 311 (04): : H1051 - H1062
  • [32] Phospholamban inhibits Ca2+ pump oligomerization and intersubunit free energy exchange leading to activation of cardiac muscle SERCA2a
    Mahaney, JE
    Albers, RW
    Kutchai, H
    Froehlich, JP
    NA,K-ATPASE AND RELATED CATION PUMPS: STRUCTURE, FUNCTION, AND REGULATORY MECHANISMS, 2003, 986 : 338 - 340
  • [33] Deubiquitinase JOSD2 improves calcium handling and attenuates cardiac hypertrophy and dysfunction by stabilizing SERCA2a in cardiomyocytes
    Jibo Han
    Zimin Fang
    Bingjiang Han
    Bozhi Ye
    Wante Lin
    Yucheng Jiang
    Xue Han
    Xu Wang
    Gaojun Wu
    Yi Wang
    Guang Liang
    Nature Cardiovascular Research, 2023, 2 : 764 - 777
  • [34] Heterozygous disruption of SERCA2a is not associated with impairment of cardiac performance in humans: implications for SERCA2a as a therapeutic target in heart failure
    Mayosi, BM
    Kardos, A
    Davies, CH
    Gumedze, F
    Hovnanian, A
    Burge, S
    Watkins, H
    HEART, 2006, 92 (01) : 105 - 109
  • [35] Deubiquitinase JOSD2 improves calcium handling and attenuates cardiac hypertrophy and dysfunction by stabilizing SERCA2a in cardiomyocytes
    Han, Jibo
    Fang, Zimin
    Han, Bingjiang
    Ye, Bozhi
    Lin, Wante
    Jiang, Yucheng
    Han, Xue
    Wang, Xu
    Wu, Gaojun
    Wang, Yi
    Liang, Guang
    NATURE CARDIOVASCULAR RESEARCH, 2023, 2 (08): : 764 - +
  • [36] Ablation Of Phospholamban And Sarcolipin Has A Deleterious Effect On SERCA Pump Activity And Cardiac Contractility
    Shanmugam, Mayilvahanan
    Gao, Shumin
    Kranias, Evangelia
    Periasamy, Muthu
    Babu, Gopal J.
    CIRCULATION, 2008, 118 (18) : S431 - S431
  • [37] Cardiac gene therapy with SERCA2a: From bench to bedside
    Gwathmey, Judith K.
    Yerevanian, Alexan I.
    Hajjar, Roger J.
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2011, 50 (05) : 803 - 812
  • [38] SERCA2a, Phospholamban, Sarcolipin, and Ryanodine Receptors Gene Expression in Children with Congenital Heart Defects
    Simona Vittorini
    Simona Storti
    Maria Serena Parri
    Alfredo Giuseppe Cerillo
    Aldo Clerico
    Molecular Medicine, 2007, 13 : 105 - 111
  • [39] Cardiac SERCA2A/B: Therapeutic targets for heart failure
    Shareef, Mohammad Abrar
    Anwer, Lucman A.
    Poizat, Coralie
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2014, 724 : 1 - 8
  • [40] SERCA2a, phospholamban, sarcolipin, and ryanodine receptors gene expression in children with congenital heart defects
    Vittorini, Simona
    Storti, Simona
    Parri, Maria Serena
    Cerillo, Alfredo Giuseppe
    Clerico, Aldo
    MOLECULAR MEDICINE, 2007, 13 (1-2) : 105 - 111
12345