Treatment of latent tuberculosis infection in patients aged ≥35 years

被引：28
|
作者：
Gilroy, SA
Rogers, MAM
Blair, DC
机构：
[1] SUNY Upstate Med Univ, Dept Med, Div Infect Dis, Syracuse, NY 13210 USA
[2] SUNY Upstate Med Univ, Dept Epidemiol, Syracuse, NY 13210 USA
来源：
CLINICAL INFECTIOUS DISEASES | 2000年 / 31卷 / 03期
关键词：
D O I：
10.1086/314037
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Treating patients aged greater than or equal to 35 years for tuberculosis infection has been controversial because of the hepatotoxic effects of isoniazid. A 2-year retrospective cohort study of outpatient medical records determined the completion rate in this age group and identified risk factors associated with isoniazid-associated hepatotoxicity. Isoniazid preventative therapy was well tolerated. However, toxicity occurred in women receiving concomitant medications and men who used alcohol.
引用
收藏
页码：826 / 829
页数：4
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