Oncogenic Kras activation in gastric adenocarcinoma promotes cancer stem cell phenotypes including metastasis & chemotherapy resistance

被引:0
|
作者
Yoon, Changhwan
Chang, Kevin K.
Till, Jacob
Ryeom, Sandra W.
Yoon, Sam S.
机构
关键词
D O I
10.1158/1538-7445.AM2017-2897
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2897
引用
收藏
页数:2
相关论文
共 50 条
  • [31] JAK-STAT signalling controls cancer stem cell properties including chemotherapy resistance in myxoid liposarcoma
    Dolatabadi, Soheila
    Jonasson, Emma
    Linden, Malin
    Fereydouni, Bentolhoda
    Backsten, Karin
    Nilsson, Malin
    Martner, Anna
    Forootan, Amin
    Fagman, Henrik
    Landberg, Goran
    Aman, Pierre
    Stahlberg, Anders
    INTERNATIONAL JOURNAL OF CANCER, 2019, 145 (02) : 435 - 449
  • [32] Insight into the molecular mechanisms of gastric cancer stem cell in drug resistance of gastric cancer
    Xiong, Jixian
    Zhang, Tiantian
    Lan, Penglin
    Zhang, Shuhong
    Fu, Li
    CANCER DRUG RESISTANCE, 2022, 5 (03) : 794 - 813
  • [33] Cancer stem cell phenotypes determine mechanisms of resistance to targeted therapies
    George, Joshy
    Chen, Yaohui
    Yamamoto, Keiko
    Adamson, Scott
    Chuang, Jeff
    Yun, Kyuson
    CANCER RESEARCH, 2018, 78 (13)
  • [34] Oncogenic KRAS activates an embryonic stem cell-like program in human colon cancer initiation
    Le Rolle, Anne-France
    Chiu, Thang K.
    Zeng, Zhaoshi
    Shia, Jinru
    Weiser, Martin R.
    Paty, Philip B.
    Chiu, Vi K.
    ONCOTARGET, 2016, 7 (03) : 2159 - 2174
  • [35] Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
    Brandt, Raphael
    Sell, Thomas
    Luethen, Mareen
    Uhlitz, Florian
    Klinger, Bertram
    Riemer, Pamela
    Giesecke-Thiel, Claudia
    Schulze, Silvia
    El-Shimy, Ismail Amr
    Kunkel, Desiree
    Fauler, Beatrix
    Mielke, Thorsten
    Mages, Norbert
    Herrmann, Bernhard G.
    Sers, Christine
    Bluethgen, Nils
    Morkel, Markus
    NATURE COMMUNICATIONS, 2019, 10 (1)
  • [36] Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium
    Raphael Brandt
    Thomas Sell
    Mareen Lüthen
    Florian Uhlitz
    Bertram Klinger
    Pamela Riemer
    Claudia Giesecke-Thiel
    Silvia Schulze
    Ismail Amr El-Shimy
    Desiree Kunkel
    Beatrix Fauler
    Thorsten Mielke
    Norbert Mages
    Bernhard G. Herrmann
    Christine Sers
    Nils Blüthgen
    Markus Morkel
    Nature Communications, 10
  • [37] Downregulation of CDH11 Promotes Metastasis and Resistance to Paclitaxel in Gastric Cancer Cells
    Yang, Zhongyin
    Yan, Chao
    Yu, Zhenjia
    He, Changyu
    Li, Jianfang
    Li, Chen
    Yan, Min
    Liu, Bingya
    Wu, Yingli
    Zhu, Zhenggang
    JOURNAL OF CANCER, 2021, 12 (01): : 65 - 75
  • [38] Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma
    Yoon, Changhwan
    Cho, Soo-Jeong
    Chang, Kevin K.
    Park, Do Joong
    Ryeom, Sandra W.
    Yoon, Sam S.
    MOLECULAR CANCER RESEARCH, 2017, 15 (08) : 1106 - 1116
  • [39] PARG Promotes Esophagus Cancer Cell Metastasis by Activation of the Wnt/β-Catenin Pathway
    Jiaxin Yan
    Yehan Zhou
    Yalan Wang
    Yang Liu
    Biochemical Genetics, 2024, 62 : 761 - 774
  • [40] PARG Promotes Esophagus Cancer Cell Metastasis by Activation of the Wnt/ß-Catenin Pathway
    Yan, Jiaxin
    Zhou, Yehan
    Wang, Yalan
    Liu, Yang
    BIOCHEMICAL GENETICS, 2024, 62 (02) : 761 - 774