Obstacles to improving outcomes in the treatment of uveal melanoma

被引：19

作者：

Tsai, Katy K. ^{[1
]}

Bollin, Kathryn B. ^{[2
]}

Patel, Sapna P. ^{[3
]}

机构：

[1] Univ Calif San Francisco, Cutaneous Oncol, Hellen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

[2] Scripps Clin, Div Hematol & Oncol, La Jolla, CA 92037 USA

[3] Univ Texas MD Anderson Canc Ctr, Dept Melanoma Med Oncol, Houston, TX 77030 USA

来源：

CANCER | 2018年 / 124卷 / 13期

基金：

美国国家卫生研究院;

关键词：

barriers; challenges; outcomes; success; therapy; treatment; trials; uveal melanoma; INTRAARTERIAL HEPATIC FOTEMUSTINE; DEPENDENT PROBE AMPLIFICATION; GENE-EXPRESSION PROFILE; LIVER METASTASES; CHOROIDAL MELANOMA; DOUBLE-BLIND; PROGNOSTIC IMPLICATIONS; UNTREATED MELANOMA; COMPLETE RESECTION; TUMOR DIAMETER;

D O I：

10.1002/cncr.31284

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The rate of advances in uveal melanoma has not kept pace with the rate of advances in cutaneous melanoma. Many patients lack access to or knowledge of specialty centers, and integrated multidisciplinary care between ophthalmology, radiation oncology, and medical oncology is far from the norm. This treatment isolation leads to limited communication about novel clinical trial opportunities. Clinical trials themselves are not widely available, and a lack of robust funding limits rapid and complete investigations. This review outlines the obstacles to success in uveal melanoma management and highlights strategies for overcoming these challenges. (C) 2018 American Cancer Society.

引用

页码：2693 / 2703

页数：11

共 50 条

[31] TREATMENT OF METASTATIC UVEAL MELANOMA - REVIEW AND RECOMMENDATIONS
ALBERT, DM
NIFFENEGGER, AS
WILLSON, JKV
SURVEY OF OPHTHALMOLOGY, 1992, 36 (06) : 429 - 438
[32] Immunoembolization for the Treatment of Uveal Melanoma Hepatic Metastases
Gonsalves, Carin F.
SEMINARS IN INTERVENTIONAL RADIOLOGY, 2024, 41 (01) : 20 - 26
[33] Leksell gamma knife treatment of uveal melanoma
Simonová, G
Novotny, J
Liscák, R
Pilbauer, J
JOURNAL OF NEUROSURGERY, 2002, 97 : 635 - 639
[34] Time to treatment of uveal melanoma in the United Kingdom
Bertil Damato
Eye, 2001, 15 : 155 - 158
[35] Treatment of uveal melanoma: an oncologist's view
Piperno-Neumann, S.
ACTA OPHTHALMOLOGICA, 2018, 96 : 96 - 96
[36] Pembrolizumab for the treatment of uveal melanoma: A case series
Jansen, Yanina Jeanne Leona
Seremet, Teofila
Neyns, Bart
RARE TUMORS, 2020, 12
[37] Uveal Melanoma: Trends in Incidence, Treatment, and Survival
Singh, Arun D.
Turell, Mary E.
Topham, Allan K.
OPHTHALMOLOGY, 2011, 118 (09) : 1881 - 1885
[38] CyberKnifeA®: new treatment option for uveal melanoma
Mor, J. M.
Semrau, R.
Baus, W.
Koch, K. R.
Schaub, F.
Cursiefen, C.
Marnitz, S.
Heindl, L. M.
OPHTHALMOLOGE, 2018, 115 (04): : 302 - 308
[39] Current and emerging treatment options for uveal melanoma
Pereira, Patricia Rusa
Odashiro, Alexandre Nakao
Lim, Li-Anne
Miyamoto, Cristina
Blanco, Paula L.
Odashiro, Macanori
Maloney, Shawn
De Souza, Dominique F.
Burnier, Miguel N., Jr.
CLINICAL OPHTHALMOLOGY, 2013, 7 : 1669 - 1682
[40] Treatment of uveal melanoma: where are we now?
Yang, Jessica
Manson, Daniel K.
Marr, Brian P.
Carvajal, Richard D.
THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2018, 10

← 1 2 3 4 5 →