NKG2A checkpoint receptor expression on tumor-infiltrating CD8+ T cells restrains efficacy of immunotherapy

被引:0
|
作者
van Hall, Thorbald
van Montfoort, Nadine
Piersma, Sytse
Sluijter, Marjolein
Welters, Marij J.
Andre, Pascale
Wagtmann, Nicolai
van der Burg, Sjoerd H.
机构
关键词
D O I
10.1158/1538-7445.AM2017-2999
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
2999
引用
收藏
页数:2
相关论文
共 50 条
  • [21] The inhibitory receptor NKG2A acts as a checkpoint on CD8 T cells in the context of cancer vaccines.
    van Hall, Thorbald
    van Montfoort, Nadine
    Borst, Linda
    Korrer, Michael J.
    Kim, Young
    Andre, Pascale
    Wagtmann, Nicolai
    Piersma, Sytse
    van der Burg, Sjoerd H.
    CANCER IMMUNOLOGY RESEARCH, 2020, 8 (04) : 81 - 81
  • [22] CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells-Letter
    Thelen, Martin
    Lechner, Axel
    Wennhold, Kerstin
    von Bergwelt-Baildon, Michael
    Schloesser, Hans A.
    CANCER RESEARCH, 2018, 78 (17) : 5173 - 5174
  • [23] CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8+ T Cells-Response
    Canale, Fernando P.
    Ramello, Maria C.
    Nunez, Nicolas
    Bossio, Sabrina N.
    Piaggio, Eliane
    Gruppi, Adriana
    Rodriguez, Eva V. Acosta
    Montes, Carolina L.
    CANCER RESEARCH, 2018, 78 (17) : 5175 - 5175
  • [24] Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells
    Cho, Jae-Ho
    Kim, Hee-Ok
    Webster, Kylie
    Palendira, Mainthan
    Hahm, Bumsuk
    Kim, Kyu-Sik
    King, Cecile
    Tangye, Stuart G.
    Sprent, Jonathan
    BLOOD, 2011, 118 (01) : 116 - 128
  • [25] Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells
    Mognol, Giuliana P.
    Spreafico, Roberto
    Wong, Victor
    Scott-Browne, James P.
    Togher, Susan
    Hoffmann, Alexander
    Hogan, Patrick G.
    Rao, Anjana
    Trifari, Sara
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017, 114 (13) : E2776 - E2785
  • [26] NKG2A expression on tumor reactive CD8 T cells is induced by IL-12
    Fesneau, Olivier
    Rosales, Wesley
    Samson, Kimberly
    Rajamanickan, Venkatesh
    Haugh, William
    Huang, Jianguo
    Duhen, Thomas
    JOURNAL OF IMMUNOLOGY, 2024, 212 (01):
  • [27] Immune Checkpoint Inhibitor-induced Reinvigoration of Tumor-infiltrating CD8+ T Cells is Determined by Their Differentiation Status in Glioblastoma
    Park, Junsik
    Kwon, Minsuk
    Kim, Kyung Hwan
    Kim, Tae-Shin
    Hong, Seon-Hui
    Kim, Chang Gon
    Kang, Seok-Gu
    Moon, Ju Hyung
    Kim, Eui Hyun
    Park, Su-Hyung
    Chang, Jong Hee
    Shin, Eui-Cheol
    CLINICAL CANCER RESEARCH, 2019, 25 (08) : 2549 - 2559
  • [28] Expression of CD94-NKG2A inhibitory receptor is restricted to a subset of CD8+ T cells
    Braud, VM
    Aldemir, H
    Breart, B
    Ferlin, WG
    TRENDS IN IMMUNOLOGY, 2003, 24 (04) : 162 - 164
  • [29] Functions of NKG2D in CD8+ T cells: an opportunity for immunotherapy
    Kushal Prajapati
    Cynthia Perez
    Lourdes Beatriz Plaza Rojas
    Brianna Burke
    Jose A Guevara-Patino
    Cellular & Molecular Immunology, 2018, 15 : 470 - 479
  • [30] NKG2A Immune Checkpoint in Vδ2 T Cells: Emerging Application in Cancer Immunotherapy
    Cazzetta, Valentina
    Depierreux, Delphine
    Colucci, Francesco
    Mikulak, Joanna
    Mavilio, Domenico
    CANCERS, 2023, 15 (04)