Development of T cell mediated gene therapy for correction of humoral and cytotoxic defects in X-linked lymphoproliferative disease (XLP)

被引：0
|
作者：
Panchal, Neelam [1 ]
Houghton, Benjamin [1 ]
Diez, Begona [1 ]
Thrasher, Adrian [1 ,2 ]
Gaspar, Bobby [1 ,2 ]
Booth, Claire [1 ,2 ]
机构：
[1] UCL GOSH Inst Child Hlth, Mol & Cellular Immunol Sect, London, England
[2] Great Ormond St Hosp Sick Children, Dept Paediat Immunol, London, England
来源：
HUMAN GENE THERAPY | 2017年 / 28卷 / 08期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
FB02
引用
收藏
页码：A10 / A11
页数：2
相关论文
共 50 条
  • [31] CORRELATION OF LYMPHOCYTE FUNCTION WITH ABNORMAL T-CELL SUBSETS IN A MALE WITH X-LINKED LYMPHOPROLIFERATIVE SYNDROME (XLP)
    YETZ, J
    LIPSCOMB, H
    BECHTOLD, T
    ZELKOWITZ, L
    PURTILO, DT
    FEDERATION PROCEEDINGS, 1983, 42 (04) : 950 - 950
  • [32] CORRECTION OF X-LINKED LYMPHOPROLIFERATIVE DISEASE BY STEM-CELL TRANSPLANTATION - REPLY
    VOWELS, MR
    DUFFY, B
    LAMPOTANG, R
    FORD, D
    NEW ENGLAND JOURNAL OF MEDICINE, 1994, 330 (16): : 1159 - 1159
  • [33] HIGH-RESOLUTION MAPPING OF PROBES NEAR THE X-LINKED LYMPHOPROLIFERATIVE DISEASE (XLP) LOCUS
    WU, BL
    MILUNSKY, A
    NELSON, D
    SCHMECKPEPER, B
    PORTA, G
    SCHLESSINGER, D
    SKARE, J
    GENOMICS, 1993, 17 (01) : 163 - 170
  • [34] TALEN-mediated genome editing via AAV6 donor in T cells for the treatment of X-linked lymphoproliferative disease (XLP)
    Houghton, B. C.
    Mussolino, C.
    Cathomen, T.
    Gaspar, H. B.
    Thrasher, A. J.
    Booth, C.
    HUMAN GENE THERAPY, 2017, 28 (12) : A52 - A52
  • [35] An X-linked lymphoproliferative syndrome (XLP) caused by mutations in the inhibitor-of-apoptosis gene XIAP
    Rigaud, Stephanie
    Latour, Sylvain
    M S-MEDECINE SCIENCES, 2007, 23 (03): : 235 - 237
  • [36] Factors involved in the generation of memory CD8+ T cells in patients with X-linked lymphoproliferative disease (XLP)
    Belmonte, L.
    Parodi, C.
    Bare, P.
    Malbran, A.
    Ruibal-Ares, B.
    de Bracco, Maria M. de E.
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2007, 147 (03): : 456 - 464
  • [37] EVALUATION OF FAMILIES WHEREIN A SINGLE MALE MANIFESTS A PHENOTYPE OF X-LINKED LYMPHOPROLIFERATIVE DISEASE (XLP)
    GRIERSON, HL
    SKARE, J
    CHURCH, J
    SILBERMAN, T
    DAVIS, JR
    KOBRINSKY, N
    MCGREGOR, R
    ISRAELS, S
    MCCARTY, J
    ANDREWS, LG
    BLECHA, T
    ERDMAN, S
    OBRINGER, A
    SCHARNHORST, D
    PURTILO, DT
    AMERICAN JOURNAL OF MEDICAL GENETICS, 1993, 47 (04): : 458 - 463
  • [38] The X-linked lymphoproliferative disease gene product SAP associates with PIX and participates in T cell activation
    Wu, Jun
    JOURNAL OF IMMUNOLOGY, 2007, 178
  • [39] X-LINKED LYMPHOPROLIFERATIVE DISEASE (XLP) AS A MODEL OF EPSTEIN-BARR VIRUS-INDUCED IMMUNOPATHOLOGY
    PURTILO, DT
    SPRINGER SEMINARS IN IMMUNOPATHOLOGY, 1991, 13 (02): : 181 - 197
  • [40] SAP gene transfer restores cellular and humoral immune function in a murine model of X-linked lymphoproliferative disease
    Rivat, Christine
    Booth, Claire
    Alonso-Ferrero, Maria
    Blundell, Michael
    Sebire, Neil J.
    Thrasher, Adrian J.
    Gaspar, H. Bobby
    BLOOD, 2013, 121 (07) : 1073 - 1076
12345