Identification of a novel small molecule inhibitor that targets HIV-1 envelope maturation

被引:0
|
作者
Jimenez, Judith [1 ]
Cao, Joan [1 ]
Jackson, Lynn [1 ]
Peng, Qinghai [1 ]
Wu, Hua [1 ]
Isaacson, Jason [1 ]
Butler, Scott [1 ]
Patick, Amy K. [1 ]
Blair, Wade S. [1 ]
机构
[1] Pfizer Global Res & Dev, La Jolla, CA USA
关键词
D O I
10.1016/j.antiviral.2007.01.009
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
1
引用
收藏
页码:A27 / A27
页数:1
相关论文
共 50 条
  • [21] A Small Molecule, ACAi-028, with Anti-HIV-1 Activity Targets a Novel Hydrophobic Pocket on HIV-1 Capsid
    Chia, Travis
    Nakamura, Tomofumi
    Amano, Masayuki
    Takamune, Nobutoki
    Matsuoka, Masao
    Nakata, Hirotomo
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2021, 65 (10)
  • [22] HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat
    Axel Fun
    Noortje M van Maarseveen
    Jana Pokorná
    Renée EM Maas
    Pauline J Schipper
    Jan Konvalinka
    Monique Nijhuis
    Retrovirology, 8
  • [23] HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat
    Fun, Axel
    van Maarseveen, Noortje M.
    Pokorna, Jana
    Maas, Renee E. M.
    Schipper, Pauline J.
    Konvalinka, Jan
    Nijhuis, Monique
    RETROVIROLOGY, 2011, 8
  • [24] Virtual screening based identification of novel small-molecule inhibitors targeted to the HIV-1 capsid
    Curreli, Francesca
    Zhang, Hongtao
    Zhang, Xihui
    Pyatkin, Ilya
    Victor, Zagorodnikov
    Altieri, Andrea
    Debnath, Asim K.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2011, 19 (01) : 77 - 90
  • [25] Sealing the Envelope-the HIV-1 Envelope Glycoproteins as Targets for Therapeutics and Vaccines
    Sanders, Rogier W.
    Berkhout, Ben
    CURRENT PHARMACEUTICAL DESIGN, 2010, 16 (33) : 3699 - 3700
  • [26] IDENTIFICATION OF A NOVEL SMALL MOLECULE HIF-1A TRANSLATION INHIBITOR
    Narita, Takuhito
    Yin, Shaoman
    Gelin, Christine F.
    Nicolaou, K. C.
    Van Meir, Erwin G.
    NEURO-ONCOLOGY, 2009, 11 (06) : 946 - 946
  • [27] Identification of a Novel Small Molecule HIF-1α Translation Inhibitor
    Narita, Takuhito
    Yin, Shaoman
    Gelin, Christine F.
    Moreno, Carlos S.
    Yepes, Manuel
    Nicolaou, K. C.
    Van Meir, Erwin G.
    CLINICAL CANCER RESEARCH, 2009, 15 (19) : 6128 - 6136
  • [28] Trilobatin as an HIV-1 entry inhibitor targeting the HIV-1 Gp41 envelope
    Yin, Shuwen
    Zhang, Xuanxuan
    Lai, Fangyuan
    Liang, Taizhen
    Wen, Jiayong
    Lin, Wanying
    Qiu, Jiayin
    Liu, Shuwen
    Li, Lin
    FEBS LETTERS, 2018, 592 (13) : 2361 - 2377
  • [29] Identification of a Novel Acylguanidine-based Inhibitor of HIV-1 Replication
    Mwimanzi, Philip M.
    Tietjen, Ian
    Shahid, Aniqa
    Miller, Scott C.
    Fedida, David
    Brummer, Zabrin
    Brockman, Mark
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2014, 30 : A205 - A205
  • [30] Identification of small molecule modulators of HIV-1 Tat and Rev protein accumulation
    Balachandran, Ahalya
    Wong, Raymond
    Stoilov, Peter
    Pan, Sandy
    Blencowe, Benjamin
    Cheung, Peter
    Harrigan, P. Richard
    Cochrane, Alan
    RETROVIROLOGY, 2017, 14