Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in Germany

被引:28
|
作者
Boehler, S. [1 ]
Scharnagl, H.
Freisinger, F.
Stojakovic, T.
Glaesmer, H.
Klotsche, J.
Pieper, L.
Pittrow, D.
Kirch, W.
Schneider, H.
Stalla, G. K.
Lehnert, H.
Zeiher, A. M.
Silber, S.
Koch, U.
Ruf, G.
Maerz, W.
Wittchen, H-U.
机构
[1] Tech Univ Dresden, Inst Clin Pharmacol, Res Federat Publ Hlth Saxony, D-8027 Dresden, Germany
[2] Tech Univ Dresden, Inst Clin Psychol & Psychotherapy, D-8027 Dresden, Germany
[3] Med Univ Graz, Clin Inst Med & Chem Lab Diagnost, Graz, Austria
[4] Max Planck Inst Psychiat, Dept Endocrinol, D-80804 Munich, Germany
[5] Univ Magdeburg, Dept Endocrinol & Metab Disorders, D-39106 Magdeburg, Germany
[6] Cty Univ Hosp, Warwick Med Sch, London, England
[7] Goethe Univ Frankfurt, Dept Cardiol Nephrol, D-6000 Frankfurt, Germany
[8] Soc German Cardiologists Private Practice, Munich, Germany
[9] Univ Hamburg, Hosp Eppendorf, Dept Med Psychol, D-20246 Hamburg, Germany
[10] Pfizer GmbH, Clin Res, Karlsruhe, Germany
关键词
dyslipidemia; cardiovascular risk; coronary heart disease; lipid disorders; risk factors; prevalence;
D O I
10.1016/j.atherosclerosis.2006.02.025
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives and methods: DETECT is a cross-sectional study of 55,518 unselected consecutive patients in 3188 representative primary care offices in Germany. In a random subset of 7519 patients, an extensive standardized laboratory program was undertaken. The study investigated the prevalence of cardiovascular disease, known risk factors (such as diabetes, hypertension and dyslipidemia and their co-morbid manifestation), as well as treatment patterns. The present analysis of the DETECT laboratory dataset focused on the prevalence and treatment of dyslipidemia in primary medical care in Germany. Coronary artery disease (CAD), risk categories and LDL-C target achievement rates were determined in the subset of 6815 patients according to the National Cholesterol Education Program (NCEP) ATP III Guidelines. Results: Of all patients, 54.3% had dyslipidemia. Only 54.4% of the NCEP-classified dyslipidernic patients were diagnosed as 'dyslipidemic' by their physicians. Only 27% of all dyslipidermc patients (and 40.7% of the recognized dyslipidemic patients) were treated with lipid-lowering medications, and 11.1% of all dyslipidemic patients (41.4% of the patients treated with lipid-lowering drugs) achieved their LDL-C treatment goals. In conclusion, 80.3% of patients in the sample with dyslipidernia went undiagnosed, un-treated or under-treated. (c) 2006 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:397 / 407
页数:11
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