A near-infrared AIEgen for specific imaging of lipid droplets

被引：95
|
作者：
Kang, Miaomiao [1 ,2 ,3 ]
Gu, Xinggui [1 ,2 ,4 ]
Kwok, Ryan T. K. [1 ,2 ,4 ]
Leung, Chris W. T. [1 ,2 ,4 ]
Lam, Jacky W. Y. [1 ,2 ,4 ]
Li, Feng [3 ,5 ]
Tang, Ben Zhong [1 ,2 ,4 ,6 ]
机构：
[1] Hong Kong Univ Sci & Technol, Hong Kong Branch Chinese Natl Engn, Res Ctr Tissue Restorat & Reconstruct,State Key L, Dept Chem,Inst Adv Study,Div Biomed Engn,Div Life, Kowloon, Hong Kong, Peoples R China
[2] Hong Kong Univ Sci & Technol, Inst Mol Funct Mat, Kowloon, Hong Kong, Peoples R China
[3] Sun Yat Sen Univ, Zhongshan Sch Med, Dept Neurobiol & Anat, Guangzhou 510080, Guangdong, Peoples R China
[4] HKUST Shenzhen Res Inst, 9 Yuexing 1st RD,South Area,Hitech Pk, Shenzhen 518057, Peoples R China
[5] Sun Yat Sen Univ, Zhongshan Sch Med, Guangdong Prov Key Lab Brain Funct & Dis, Guangzhou 510080, Guangdong, Peoples R China
[6] S China Univ Technol, Guangdong Innovat Res Team, SCUT HKUST Joint Res Lab, State Key Lab Luminescent Mat & Devices, Guangzhou 510640, Guangdong, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 35期
基金：
中国国家自然科学基金;
关键词：
AGGREGATION-INDUCED-EMISSION; LIGHT-UP PROBE; PHOTODYNAMIC THERAPY; ORGANIC NANOPARTICLES; LIVER-BIOPSY; MITOCHONDRIA; ENHANCEMENT; CELLS; BIOPROBES; PLASMA;
D O I：
10.1039/c6cc01797e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A new near-infrared AIE luminogen (TPE-AC) with high specificity, good biocompatibility and excellent photostability is designed and synthesized for lipid droplet (LD) imaging in cells. TPE-AC can monitor the process of LD accumulation in cells, thus making it potential for the diagnosis of early-stage fat-related diseases.
引用
收藏
页码：5957 / 5960
页数：4
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