Conditional stimulatzion of the dorsal penile/clitoral nerve may increase cystometric capacity in patients with spinal cord injury

被引:70
|
作者
Dalmose, AL [1 ]
Rijkhoff, NJM
Kirkeby, HJ
Nohr, M
Sinkjaer, T
Djurhuus, JC
机构
[1] Aarhus Univ, Hosp Skejby, DK-8200 Aarhus N, Denmark
[2] Aalborg Univ, Ctr Sensory Motor Interact, Aalborg O, Denmark
[3] Aalborg Cty Hosp, Dept Urol, Aalborg C, Denmark
[4] Arhus Univ Hosp Skejby, Dept Urol, Aarhus N, Denmark
关键词
spinal cord injuries; urodynamics; electric stimulation; peripheral nerves;
D O I
10.1002/nau.10031
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Aims: To investigate the feasibility of conditional short duration electrical stimulation of the Penile/clitoral nerve as treatment for detrusor hyperreflexia, the present study was initiated. Methods: Ten patients with spinal cord injury, 4 women and 6 men, with lesions at different levels above the sacral micturition center had a standard cystometry performed. During a subsequent cystometry, conditional short duration electrical stimulation of the penile/clitoral nerve was performed as treatment for one or more detrusor hyperreflexic contractions. Resuts: In all patients, at least one contraction (mean, 7.8; range, 1-16 contractions) was inhibited by the stimulations. The mean cystometric capacity was increased significantly by conditional electrical stimulation, from 210 mL in the control cystometries to 349 mL in the stimulation cystometries (P = 0.016). The maximal detrusor pressure during the first contraction in the control cystometries was mean 51 cm H2O, whereas the maximal pressure of the first contraction in the stimulation cystometries was reduced to mean 33 CM H2O (P = 0.045). Conclusions: The authors conclude that repeated conditional short duration electrical stimulation significantly increased cystometric capacity in patients with spinal cord injury. The increase was caused mainly by an inhibition of detrusor contractions. The need for a reliable technique for chronic bladder activity monitoring is emphasized, as it is a prerequisite for clinical application of this treatment modality. Neurourol Urodynam. 22:130-137,2003. (C) 2003 Wiley-Liss, Inc.
引用
收藏
页码:130 / 137
页数:8
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