DESIGN AND SYNTHESIS OF NOVEL MMP-2 INHIBITORS WITH HYDROXAMATE AND OXADIAZOLE UNITS AS ZINC BINDING GROUPS

被引：0
|
作者：
Puckowska, Anna [1 ,2 ]
Bruczko, Marta [1 ,3 ]
Maria Zapico, Jose [1 ]
Serra, Pilar [1 ]
Martin-Santamaria, Sonsoles [1 ]
de Pascual-Teresa, Beatriz [1 ]
Ramos, Ana [1 ]
机构：
[1] Univ San Pablo CEU, Fac Pharm, Dept Organ Chem, Madrid, Spain
[2] Med Univ Bialystok, Fac Pharm, Dept Organ Chem, Bialystok, Poland
[3] Med Univ Bialystok, Dept Med Chem, Bialystok, Poland
来源：
DRUGS OF THE FUTURE | 2009年 / 34卷
关键词：
PROGRESS;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：172 / 172
页数：1
相关论文
共 50 条
  • [21] Design and Synthesis of 2, 5-disubstituted Oxadiazole as Novel PTP1B Inhibitors
    Athare, Chandrashekhar L.
    Upasani, Chandrashekhar D.
    INTERNATIONAL JOURNAL OF PHARMACEUTICAL AND PHYTOPHARMACOLOGICAL RESEARCH, 2014, 3 (05): : 383 - 386
  • [22] Synthesis, Biological Evaluation, and Docking of Dihydropyrazole Sulfonamide Containing 2-hydroxyphenyl Moiety: A Series of Novel MMP-2 Inhibitors
    Wang, Peng-Fei
    Qiu, Han-Yue
    Baloch, Shahla Karim
    Gong, Hai-Bin
    Wang, Zhong-Chang
    Zhu, Hai-Liang
    CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 86 (06) : 1405 - 1410
  • [23] THEORETICAL STUDY ON POTENCY AND SELECTIVITY OF NOVEL NONPEPTIDE INHIBITORS OF MATRIX METALLOPROTEINASES MMP-2 AND MMP-9
    Li, Dai-Lin
    Zheng, Qing-Chuan
    Fang, Xue-Xun
    Ji, Hai-Tao
    Yang, Jin-Gang
    Zhang, Hong-Xing
    JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY, 2009, 8 (03): : 491 - 506
  • [24] Design of dual MMP-2/HDAC-8 inhibitors by pharmacophore mapping, molecular docking, synthesis and biological activity
    Halder, Amit K.
    Mallick, Sumana
    Shikha, Deep
    Saha, Achintya
    Saha, Krishna D.
    Jha, Tarun
    RSC ADVANCES, 2015, 5 (88) : 72373 - 72386
  • [25] Design, synthesis, evaluation and 3D-QSAR analysis of benzosulfonamide benzenesulfonates as potent and selective inhibitors of MMP-2
    Qiu, Han-Yue
    Wang, Zhong-Chang
    Wang, Peng-Fei
    Yan, Xiao-Qiang
    Wang, Xiao-Ming
    Yang, Yong-Hua
    Zhu, Hai-Liang
    RSC ADVANCES, 2014, 4 (74) : 39214 - 39225
  • [26] Design, synthesis, and evaluation of sultam hydroxamates as novel MMP inhibitors.
    Cherney, RJ
    Meyer, DT
    Wasserman, ZR
    Hardman, KD
    Liu, RQ
    Covington, MB
    Qian, MX
    Christ, DD
    Trzaskos, JM
    Newton, RC
    Magolda, RL
    Decicco, CP
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2003, 226 : U21 - U21
  • [27] Examination of novel zinc-binding groups for use in matrix metalloproteinase inhibitors
    Puerta, DT
    Cohen, SM
    INORGANIC CHEMISTRY, 2003, 42 (11) : 3423 - 3430
  • [28] Nε-acetyl lysine derivatives With zinc binding groups as novel HDAC inhibitors
    Wang, Fang
    Wang, Chun
    Wang, Jie
    Zou, Yefang
    Chen, Xiaoxue
    Liu, Ting
    Li, Yan
    Zhao, Yonglong
    Li, Yongjun
    He, Bin
    ROYAL SOCIETY OPEN SCIENCE, 2019, 6 (06):
  • [29] NOVEL 1,2,4-OXADIAZOLE DERIVATIVES AS SELECTIVE BUTYRYLCHOLINESTERASE INHIBITORS: DESIGN, SYNTHESIS, AND BIOLOGICAL EVALUATION
    Nazari, Maryam
    Rezaee, Elham
    Hariri, Roshanak
    Akbarzadeh, Tahmineh
    Tabatabai, Sayyed Abbas
    EXCLI JOURNAL, 2021, 20 : 907 - 921
  • [30] Synthesis and Biological Evaluation of HDAC Inhibitors With a Novel Zinc Binding Group
    He Junquan
    Wang Songsong
    Liu Xingang
    Lin Ruili
    Deng Fang
    Jia Zhong
    Zhang Chenghong
    Li Zhao
    Zhu Hongtian
    Tang Lei
    Yang Pingrong
    He Dian
    Jia Qingzhong
    Zhang Yang
    FRONTIERS IN CHEMISTRY, 2020, 8
12345