Viral mechanisms of immune evasion

被引:263
|
作者
Alcami, A
Koszinowski, UH
机构
[1] Univ Cambridge, Dept Pathol, Div Virol, Cambridge CB2 1QP, England
[2] Univ Munich, Max Von Pettenkofer Inst, Dept Virol, Gene Ctr, D-81377 Munich, Germany
基金
英国惠康基金;
关键词
D O I
10.1016/S0966-842X(00)01830-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During the millions of years they have coexisted with their hosts, viruses have learned how to manipulate host immune control mechanisms. Viral gene functions provide an overview of many relevant principles in cell biology and immunology. Our knowledge of viral gene functions must be integrated into virus-host interaction networks to understand viral pathogenesis, and could lead to new antiviral strategies and the ability to exploit viral functions as tools in medicine.
引用
收藏
页码:410 / 418
页数:9
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