We report a case of ticlopidine-induced profound neutropenia early in the course of therapy, which was manifest as a febrile systemic illness mimicking sepsis. This clinical presentation was potentially indicative of a contaminated intracoronary stent. The patient's signs and symptoms of illness promptly resolved with removal of ticlopidine, and no infection was documented. Review of indications for ticlopidine use, potential adverse effects, and monitoring recommendations are discussed.
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Tel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, IsraelTel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, Israel
Gur, H
Wartenfeld, R
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机构:Tel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, Israel
Wartenfeld, R
Tanne, D
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机构:Tel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, Israel
Tanne, D
Solomon, F
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机构:Tel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, Israel
Solomon, F
Sidi, Y
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机构:Tel Aviv Univ, Sackler Fac Med, Chaim Sheba Med Ctr, Dept Med C, IL-52621 Tel Hashomer, Israel