Margin Analysis Squamous Cell Carcinoma of the Oropharynx

被引：11
|
作者：
Sim, Felix W. [1 ]
Xiao, Hong D. [2 ]
Bell, R. Bryan [1 ]
机构：
[1] Providence Portland Med Ctr, Providence Canc Ctr, Head & Neck Inst, 4805 Northeast Glisan St,Suite 6N50, Portland, OR 97213 USA
[2] Providence Portland Med Ctr, Dept Pathol, 4805 Northeast Glisan St,Suite 6N50, Portland, OR 97213 USA
来源：
ORAL AND MAXILLOFACIAL SURGERY CLINICS OF NORTH AMERICA | 2017年 / 29卷 / 03期
关键词：
Surgical margins; Oropharyngeal cancer; Squamous cell carcinoma; Prognosis; Local control; Head and neck; HPV; TRANSORAL ROBOTIC SURGERY; TUMOR-INFILTRATING LYMPHOCYTES; HUMAN-PAPILLOMAVIRUS; LASER MICROSURGERY; ORGAN PRESERVATION; TONGUE BASE; IN-VIVO; HEAD; STAGE; SURVIVAL;
D O I：
10.1016/j.coms.2017.03.004
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Because of the common shared risk factors of smoking and heavy alcohol consumption, literature involving oropharyngeal squamous cell carcinoma (OPSCC) is often combined with oral squamous cell carcinoma. Human papilloma virus is now confirmed to be a major risk factor of OPSCC with its distinct epidemiology and favorable treatment outcome. The impact of adjuvant chemoradiation in the setting of positive surgical margins remains unclear but is likely influenced by tumor biology. This article reviews the tumor biology of OPSCC and summarizes recent findings on outcomes following surgical treatment of OPSCC.
引用
收藏
页码：269 / +
页数：13
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