A partially described inverse eigenvalue problem and an associated optimal approximation problem for generalized K-centrohermitian matrices are considered. It is shown under which conditions the inverse eigenproblem has a solution. An expression of its general solution is given. In case a solution of the inverse eigenproblem exists, the optimal approximation problem can be solved. The formula of its unique solution is given. (c) 2006 Elsevier B.V. All rights reserved.