Inhibition of HIV-1 reverse transcriptase by methanol extracts of commercial herbs and spices

被引：0
|
作者：
Kobayashi, Y [1 ]
Watanabe, M [1 ]
Ogihara, J [1 ]
Kato, J [1 ]
Oishi, K [1 ]
机构：
[1] Nihon Univ, Fac Bioresource Sci, Fujisawa, Kanagawa 2528510, Japan
来源：
JOURNAL OF THE JAPANESE SOCIETY FOR FOOD SCIENCE AND TECHNOLOGY-NIPPON SHOKUHIN KAGAKU KOGAKU KAISHI | 2000年 / 47卷 / 08期
关键词：
D O I：
暂无
中图分类号：
TS2 [食品工业];
学科分类号：
0832 ;
摘要：
Fifty four samples of methanol-extract prepared from commercial herbs and spices were assayed their HIV-1 reverse transcriptase-inhibitory activity. Rosemary, cinnamon, sage, and cao guo showed strong inhibition with IC50 values of 4.2, 4.3, 6.0 and 6.5 mu g/ml, respectively. So far examined with TLC, the methanol extracts did not contain detectable amount of tannins and flavonoids.
引用
收藏
页码：642 / 645
页数：4
相关论文
共 50 条
  • [1] Inhibition of HIV-1 reverse transcriptase and HIV-1 integrase and antiviral activity of Korean seaweed extracts
    Ahn, MJ
    Yoon, KD
    Kim, CY
    Min, SY
    Kim, YU
    Kim, HJ
    Kim, JH
    Shin, CG
    Lee, CK
    Kim, TG
    Kim, SH
    Huh, H
    Kim, J
    JOURNAL OF APPLIED PHYCOLOGY, 2002, 14 (05) : 325 - 329
  • [2] Inhibition of HIV-1 reverse transcriptase and HIV-1 integrase and antiviral activity of Korean seaweed extracts
    Mi-Jeong Ahn
    Kee-Dong Yoon
    Chul Young Kim
    So-Young Min
    Yong-ung Kim
    Hyun Jin Kim
    Jeong Ha Kim
    Cha-Gyun Shin
    Chong-Kyo Lee
    Tae Gyun Kim
    Seung Hee Kim
    Hoon Huh
    Jinwoong Kim
    Journal of Applied Phycology, 2002, 14 : 325 - 329
  • [3] A comparison of HIV-1 integrase inhibition by aqueous and methanol extracts of Chinese medicinal herbs
    Au, TK
    Lam, TL
    Ng, TB
    Fong, WP
    Wan, DCC
    LIFE SCIENCES, 2001, 68 (14) : 1687 - 1694
  • [4] A novel mechanism for inhibition of HIV-1 reverse transcriptase
    Skillman, AG
    Maurer, KW
    Roe, DC
    Stauber, MJ
    Eargle, D
    Ewing, TJA
    Muscate, A
    Davioud-Charvet, E
    Medaglia, MV
    Fisher, RJ
    Arnold, E
    Gao, HQ
    Buckheit, R
    Boyer, PL
    Hughes, SH
    Kuntz, ID
    Kenyon, GL
    BIOORGANIC CHEMISTRY, 2002, 30 (06) : 443 - 458
  • [5] Theoretical studies of HIV-1 reverse transcriptase inhibition
    Swiderek, Katarzyna
    Marti, Sergio
    Moliner, Vicent
    PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2012, 14 (36) : 12614 - 12624
  • [6] Inhibition of HIV-1 reverse transcriptase and HIV-1 replication by Calophyllum coumarins and xanthones
    Dharmaratne, HRW
    Tan, GT
    Marasinghe, GPK
    Pezzuto, JM
    PLANTA MEDICA, 2002, 68 (01) : 86 - 87
  • [7] Inhibition of HIV-1 Reverse Transcriptase Dimerization by Small Molecules
    Tintori, Cristina
    Corona, Angela
    Esposito, Francesca
    Brai, Annalaura
    Grandi, Nicole
    Ceresola, Elisa Rita
    Clementi, Massimo
    Canducci, Filippo
    Tramontano, Enzo
    Botta, Maurizio
    CHEMBIOCHEM, 2016, 17 (08) : 683 - 688
  • [8] OBSERVATIONS ON THE INHIBITION OF HIV-1 REVERSE-TRANSCRIPTASE BY CATECHINS
    MOORE, PS
    PIZZA, C
    BIOCHEMICAL JOURNAL, 1992, 288 : 717 - 719
  • [9] Inhibition of HIV-1 reverse transcriptase and its binding to HIV-1 integrase by modified oligonucleotides
    Korolev, S.
    Kondrashina, O.
    Lysenko, E.
    Gottikh, M.
    FEBS JOURNAL, 2013, 280 : 84 - 85
  • [10] HIV-1 reverse transcriptase inhibitors
    El Safadi, Yazan
    Vivet-Boudou, Valerie
    Marquet, Roland
    APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 2007, 75 (04) : 723 - 737
12345