Pregabalin (Lyrica) in the treatment of essential tremor

被引：15
|
作者：
Zesiewicz, Theresa A. [1 ]
Ward, Christopher L. [1 ]
Hauser, Robert A. [1 ]
Campbell, Jessica A. Pease [1 ]
Sullivan, Kelly L. [1 ]
机构：
[1] Univ S Florida, Dept Psychiat, Natl Parkinsons Fdn Ctr Excellence, Neurosci Program,Dept Mol Therapeut,Dept Neurol,P, Tampa, FL 33612 USA
来源：
MOVEMENT DISORDERS | 2007年 / 22卷 / 01期
关键词：
essential tremor; pregabalin; Lyrica; gammaaminobutyric acid; tremor;
D O I：
10.1002/mds.21211
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report on 2 essential tremor patients who experienced marked improvement in upper extremity tremor with the use of pregabalin (Lyrica, PGB). On PGB 200 mg/day, tremor amplitude was reduced by at least 40% in the worst affected hand in both patients as measured by accelerometry. Both patients also reported moderate reduction in tremor on the Clinical Global Impression Scale, and Fahn-Tolosa-Marin Part I scores were markedly improved. (C) 2006 Movement Disorder Society.
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页码：139 / 141
页数：3
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