Interleukin-17: friend or foe in atherosclerosis?

被引：47
|
作者：
Taleb, Soraya [2 ,3 ]
Tedgui, Alain [2 ,3 ]
Mallat, Ziad [1 ,2 ,3 ]
机构：
[1] Univ Cambridge, Addenbrookes Hosp, Dept Med, Div Cardiovasc Med, Cambridge CB2 2QQ, England
[2] INSERM, U970, Paris, France
[3] Paris Descartes Univ, Paris, France
来源：
CURRENT OPINION IN LIPIDOLOGY | 2010年 / 21卷 / 05期
关键词：
atherosclerosis; interleukin-17; lymphocytes; T(H)17 CELL-DIFFERENTIATION; ROR-GAMMA-T; EXPERIMENTAL AUTOIMMUNE UVEITIS; SMOOTH-MUSCLE-CELLS; GROWTH-FACTOR-BETA; DEFICIENT MICE; MYOCARDIAL-INFARCTION; ASSOCIATION ANALYSIS; EFFECTOR RESPONSE; INTERFERON-GAMMA;
D O I：
10.1097/MOL.0b013e32833dc7f9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
IL-17 seems to have a modulatory role in atherosclerosis. Future studies are needed to better determine the molecular mechanisms involved in this regulation and examine whether targeting IL-17 pathway will be useful to treat cardiovascular diseases.
引用
收藏
页码：404 / 408
页数：5
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