The role of complement and Toll-like receptors in organ transplantation

被引：16
|
作者：
Lin, Tao
Zhou, Wuding
Sacks, Steven H. [1 ]
机构：
[1] Guys Hosp, Kings Coll London Sch Med, Dept Nephrol & Transplantat, London SE1 9RT, England
[2] Kings Coll Hosp London, Kings Coll London Sch Med, Dept Nephrol & Transplantat, London, England
[3] St Thomas Hosp, Kings Coll London Sch Med, Dept Nephrol & Transplantat, London, England
[4] Sichuan Univ, W China Hosp, Dept Urol, Chengdu 610064, Peoples R China
来源：
TRANSPLANT INTERNATIONAL | 2007年 / 20卷 / 06期
基金：
英国医学研究理事会; 英国惠康基金;
关键词：
complement immunity; natural Toll-like receptor transplantation; ISCHEMIA-REPERFUSION INJURY; DECAY-ACCELERATING FACTOR; ACUTE ALLOGRAFT-REJECTION; ACUTE-RENAL-FAILURE; ADAPTIVE IMMUNE-RESPONSES; DENDRITIC CELL MATURATION; TH2 EFFECTOR FUNCTIONS; CD8(+) T-CELLS; ISCHEMIA/REPERFUSION INJURY; COMPONENT C3;
D O I：
10.1111/j.1432-2277.2006.00448.x
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The innate immune system not only participates in host defence but also contributes to the control of adaptive immune responses. Complement and Toll-like receptors (TLR) are key components of innate immunity. Emerging evidence suggests their activation is involved in all major aspects of transplantation. This paper reviews the current understanding of how the complement and TLR on impact transplant injury.
引用
收藏
页码：481 / 489
页数：9
相关论文
共 50 条
  • [41] The Toll-like receptors and their role in septic shock
    Cristofaro, P
    Opal, SM
    EXPERT OPINION ON THERAPEUTIC TARGETS, 2003, 7 (05) : 603 - 612
  • [42] The Role of Toll-Like Receptors in Neuroimmunology of Alcoholism
    M. I. Airapetov
    S. O. Eresko
    A. A. Lebedev
    E. R. Bychkov
    P. D. Shabanov
    Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry, 2021, 15 : 71 - 79
  • [43] The Role of Toll-Like Receptors in Neuroimmunology of Alcoholism
    Airapetov, M. I.
    Eresko, S. O.
    Lebedev, A. A.
    Bychkov, E. R.
    Shabanov, P. D.
    BIOCHEMISTRY MOSCOW-SUPPLEMENT SERIES B-BIOMEDICAL CHEMISTRY, 2021, 15 (01) : 71 - 79
  • [44] The role of Toll-like receptors in ovarian cancer
    Gata, Vlad
    Laurentiu, Ignat Florin
    JOURNAL OF BUON, 2017, 22 (05): : 1092 - 1096
  • [45] The Role of Toll-Like Receptors in Pathogenesis of Periodontitis
    Chrzeszczyk, Dariusz
    Konopka, Tomasz
    DENTAL AND MEDICAL PROBLEMS, 2009, 46 (01) : 94 - 103
  • [46] The role of Toll-like receptors in skin diseases
    Bacharewicz, Joanna
    Reduta, Teresa
    Flisiak, Iwona
    PRZEGLAD DERMATOLOGICZNY, 2014, 101 (04): : 309 - 318
  • [47] Role of Toll-Like Receptors in Respiratory Diseases
    Crespo-Lessmann, Astrid
    Juarez-Rubio, Candido
    Plaza-Moral, Vicente
    ARCHIVOS DE BRONCONEUMOLOGIA, 2010, 46 (03): : 135 - 142
  • [48] Role of Toll-like receptors in gastrointestinal malignancies
    Fukata, M.
    Abreu, M. T.
    ONCOGENE, 2008, 27 (02) : 234 - 243
  • [49] Role of Toll-Like Receptors in Tuberculosis Infection
    Biyikli, Oguz Oben
    Baysak, Aysegul
    Ece, Gulfem
    Oz, Adnan Tolga
    Ozhan, Mustafa Hikmet
    Berdeli, Afig
    JUNDISHAPUR JOURNAL OF MICROBIOLOGY, 2016, 9 (10)
  • [50] Role of toll-like receptors in lung cancer
    Yang, Liu-Shan
    Wu, Wen-Sen
    Zhang, Fu
    Jiang, Yi
    Fan, Yue
    Fang, Heng-Xiao
    Long, Ju
    JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION, 2014, 34 (05) : 342 - 344
12345