Can Ultrasound Therapy Be an Environmental-Friendly Alternative to Non-Steroidal Anti-Inflammatory Drugs in Knee Osteoarthritis Treatment?

被引：9

作者：

Ungur, Rodica Ana ^{[1
]}

Ciortea, Viorela Mihaela ^{[1
]}

Irsay, Laszlo ^{[1
]}

Ciubean, Alina Deniza ^{[1
]}

Nasui, Bogdana Adriana ^{[2
]}

Codea, Razvan Andrei ^{[3
]}

Singurean, Victoria Emilia ^{[1
]}

Groza, Oana Bianca ^{[1
]}

Cainap, Simona ^{[4
]}

Martis , Georgiana Smaranda ^{[5
]}

Borda, Cristin ^{[3
]}

Borda, Ileana Monica ^{[1
]}

机构：

[1] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Med Specialties, Cluj Napoca 400012, Romania

[2] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Community Hlth, Cluj Napoca 400012, Romania

[3] Univ Agr Sci & Vet Med, Fac Vet Med, Cluj Napoca 400372, Romania

[4] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Mother & Child, Cluj Napoca 400012, Romania

[5] Univ Agr Sci & Vet Med Cluj Napoca, Food Engn Dept, Cluj Napoca 400509, Romania

来源：

MATERIALS | 2021年 / 14卷 / 11期

关键词：

non-steroidal anti-inflammatory drugs; ultrasound therapy; health benefits; environment pollutants; INTENSITY PULSED ULTRASOUND; HUMAN ARTICULAR CHONDROCYTES; SURFACE WATERS; MATRIX PRODUCTION; AMERICAN-COLLEGE; GENE-EXPRESSION; TERM EXPOSURE; DOUBLE-BLIND; DICLOFENAC; NAPROXEN;

D O I：

10.3390/ma14112715

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The non-steroidal anti-inflammatory drugs (NSAIDs) are the most used drugs in knee osteoarthritis (OA) treatment. Despite their efficiency in pain and inflammation alleviation, NSAIDs accumulate in the environment as chemical pollutants and have numerous genetic, morphologic, and functional negative effects on plants and animals. Ultrasound (US) therapy can improve pain, inflammation, and function in knee OA, without impact on environment, and with supplementary metabolic beneficial effects on cartilage compared to NSAIDs. These features recommend US therapy as alternative for NSAIDs use in knee OA treatment.

引用

页数：15

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