Statins and Type 2 Diabetes Mellitus: An Update After 1 Year

被引：10

作者：

Katsiki, Niki ^{[1
]}

Athyros, Vasilios G. ^{[1
]}

Karagiannis, Asterios ^{[1
]}

Mikhailidis, Dimitri P. ^{[2
,3
]}

机构：

[1] Aristotle Univ Thessaloniki, Propedeut Dept Internal Med 2, Sch Med, Hippocrat Hosp, GR-54006 Thessaloniki, Greece

[2] UCL, Dept Clin Biochem, Vasc Dis Prevent Clin, Sch Med, Royal Free Campus, London NW3 2QG, England

[3] UCL, Dept Surg, Sch Med, Royal Free Campus, London NW3 2QG, England

来源：

CURRENT PHARMACEUTICAL DESIGN | 2016年 / 22卷 / 18期

关键词：

IMPROVE-IT; diabetes mellitus; cancer; statins; new onset diabetes; ezetimibe; COLORECTAL-CANCER; PROSTATE-CANCER; POSTPRANDIAL TRIGLYCERIDES; CARDIOVASCULAR RISK; FAT INTAKE; EZETIMIBE; THERAPY; LIPOPROTEINS; MORTALITY; ASPIRIN;

D O I：

10.2174/1381612822666160125114626

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In a review [1] published in this journal in 2014 we updated the role of statin treatment in patients with type 2 diabetes mellitus (T2DM). This is an important topic because the prevalence of T2DM is increasing and this disease is associated with a high risk of cardiovascular disease (CVD) as well as microvascular complications [1]. The relationship between T2DM and statins is further complicated since these drugs can cause new onset diabetes (NOD) although there is an overall benefit in terms of preventing vascular events [1, 2]. The cost implications of T2DM in terms of quality of life as well as providing healthcare are obvious. This is a brief update of our earlier review [1] based on recently published data.

引用

页码：2723 / 2725

页数：3

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