In vitro model for inflammatory activation of human iPSC-derived astrocytes and microglia in multiple sclerosis

被引:0
|
作者
Hyvarinen, T. [1 ]
Lotila, J. [1 ]
Sukki, L. [1 ]
Konttinen, H. [2 ]
Malm, T. [2 ]
Airas, L. [3 ]
Kallio, P. [1 ]
Narkilahti, S. [1 ]
Hagman, S. [1 ]
机构
[1] Tampere Univ, Fac Med & Hlth Technol, Tampere, Finland
[2] Univ Eastern Finland, Fac Hlth Sci, Kuopio, Finland
[3] Univ Turku, Dept Clin Med, Turku, Finland
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
T14-038C
引用
收藏
页码:E458 / E459
页数:2
相关论文
共 50 条
  • [11] Human trait of microglia: iPSC-derived microglia in modeling microglial functions.
    Konttinen, H.
    Cabral-da-Silva, M. E. Castro
    Ohtonen, S.
    Shakirzyanova, A.
    Ishchenko, Y.
    Caligola, S.
    Giugno, R.
    Hernandez, D.
    Fazaludeen, F.
    Eamen, S.
    Fagerlund, I.
    Scoyni, F.
    Wojciechowski, S.
    Huber, N.
    Haapasalo, A.
    Oksanen, M.
    Propson, N.
    Schwartz, M. P.
    Graff, C.
    Lehtonen, S.
    Kanninen, K.
    Pebay, A.
    Koistinaho, J.
    Ooi, L.
    Malm, T. M.
    GLIA, 2019, 67 : E113 - E114
  • [12] Comparison of two protocols for the generation of iPSC-derived human astrocytes
    Patrycja Mulica
    Carmen Venegas
    Zied Landoulsi
    Katja Badanjak
    Sylvie Delcambre
    Maria Tziortziou
    Soraya Hezzaz
    Jenny Ghelfi
    Semra Smajic
    Jens Schwamborn
    Rejko Krüger
    Paul Antony
    Patrick May
    Enrico Glaab
    Anne Grünewald
    Sandro L. Pereira
    Biological Procedures Online, 25
  • [13] Aberrant iPSC-derived human astrocytes in Alzheimer's disease
    V C Jones
    R Atkinson-Dell
    A Verkhratsky
    L Mohamet
    Cell Death & Disease, 2017, 8 : e2696 - e2696
  • [14] Serine metabolism during differentiation of human iPSC-derived astrocytes
    Tripodi, Farida
    Motta, Zoraide
    Murtas, Giulia
    Rabattoni, Valentina
    Nonnis, Simona
    Scalvini, Francesca Grassi
    Rinaldi, Anna Maria
    Rizzi, Roberto
    Bearzi, Claudia
    Badone, Beatrice
    Sacchi, Silvia
    Tedeschi, Gabriella
    Maffioli, Elisa
    Coccetti, Paola
    Pollegioni, Loredano
    FEBS JOURNAL, 2023, 290 (18) : 4440 - 4464
  • [15] Aberrant iPSC-derived human astrocytes in Alzheimer's disease
    Jones, V. C.
    Atkinson-Dell, R.
    Verkhratsky, A.
    Mohamet, L.
    CELL DEATH & DISEASE, 2017, 8 : e2696 - e2696
  • [16] Comparison of two protocols for the generation of iPSC-derived human astrocytes
    Mulica, Patrycja
    Venegas, Carmen
    Landoulsi, Zied
    Badanjak, Katja
    Delcambre, Sylvie
    Tziortziou, Maria
    Hezzaz, Soraya
    Ghelfi, Jenny
    Smajic, Semra
    Schwamborn, Jens
    Krueger, Rejko
    Antony, Paul
    May, Patrick
    Glaab, Enrico
    Gruenewald, Anne
    Pereira, Sandro L.
    BIOLOGICAL PROCEDURES ONLINE, 2023, 25 (01)
  • [17] Using human iPSC-derived organoids to model demyelination, oligodendrocyte dysfunction and microglial toxicity in Multiple Sclerosis
    Ramesan, S.
    Mason, J.
    Rutar, M.
    Swanson, M. E.
    Turner, B.
    Gonsalvez, D.
    Barton, S. K.
    GLIA, 2023, 71 : E756 - E756
  • [18] CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
    Kun Leng
    Indigo V. L. Rose
    Hyosung Kim
    Wenlong Xia
    Wilber Romero-Fernandez
    Brendan Rooney
    Mark Koontz
    Emmy Li
    Yan Ao
    Shinong Wang
    Mitchell Krawczyk
    Julia TCW
    Alison Goate
    Ye Zhang
    Erik M. Ullian
    Michael V. Sofroniew
    Stephen P. J. Fancy
    Matthew S. Schrag
    Ethan S. Lippmann
    Martin Kampmann
    Nature Neuroscience, 2022, 25 : 1528 - 1542
  • [19] CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
    Leng, Kun
    Rose, Indigo V. L.
    Kim, Hyosung
    Xia, Wenlong
    Romero-Fernandez, Wilber
    Rooney, Brendan
    Koontz, Mark
    Li, Emmy
    Ao, Yan
    Wang, Shinong
    Krawczyk, Mitchell
    Tcw, Julia
    Goate, Alison
    Zhang, Ye
    Ullian, Erik M.
    Sofroniew, Michael, V
    Fancy, Stephen P. J.
    Schrag, Matthew S.
    Lippmann, Ethan S.
    Kampmann, Martin
    NATURE NEUROSCIENCE, 2022, 25 (11) : 1528 - +
  • [20] Human iPSC-derived retinal organoid model for in vitro toxicity screening
    Chichagova, V.
    Dorgau, B.
    de Santis, C.
    Georgiou, M.
    Carter, M.
    Hilgen, G.
    Collin, J.
    Queen, R.
    Chung, G.
    Ajeian, J.
    Moya-Molina, M.
    Kustermann, S.
    Pognan, F.
    Hewitt, P.
    Schmitt, M.
    Sernagor, E.
    Armstrong, L.
    Lako, M.
    TOXICOLOGY LETTERS, 2021, 350 : S45 - S45