In vitro model for inflammatory activation of human iPSC-derived astrocytes and microglia in multiple sclerosis

被引:0
|
作者
Hyvarinen, T. [1 ]
Lotila, J. [1 ]
Sukki, L. [1 ]
Konttinen, H. [2 ]
Malm, T. [2 ]
Airas, L. [3 ]
Kallio, P. [1 ]
Narkilahti, S. [1 ]
Hagman, S. [1 ]
机构
[1] Tampere Univ, Fac Med & Hlth Technol, Tampere, Finland
[2] Univ Eastern Finland, Fac Hlth Sci, Kuopio, Finland
[3] Univ Turku, Dept Clin Med, Turku, Finland
关键词
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
T14-038C
引用
收藏
页码:E458 / E459
页数:2
相关论文
共 50 条
  • [1] In vitro model for inflammatory activation of human iPSC-derived astrocytes
    Hyvarinen, T.
    Hagman, S.
    Veijula, K.
    Sukki, L.
    Ristola, M.
    Kallio, P.
    Narkilahti, S.
    GLIA, 2019, 67 : E584 - E584
  • [2] In vitro modeling of multiple sclerosis utilizing human iPSC-derived microglia
    Lotila, J.
    Hyvarinen, T.
    Jantti, H.
    Ohtonen, S.
    Skottman, H.
    Airas, L.
    Malm, T.
    Narkilahti, S.
    Hagman, S.
    GLIA, 2023, 71 : E947 - E947
  • [3] Co-culture of iPSC-derived microglia and iPSC-derived astrocytes: modeling multiple sclerosis white and grey matter lesion environments
    van Wageningen, T. A.
    van Dam, A. -M.
    Breve, J. J.
    Gasparotto, L.
    Heine, V. M.
    MULTIPLE SCLEROSIS JOURNAL, 2022, 28 (3_SUPPL) : 501 - 502
  • [4] Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres
    Abreu, Celina Monteiro
    Gama, Lucio
    Krasemann, Susanne
    Chesnut, Megan
    Odwin-Dacosta, Shelly
    Hogberg, Helena T.
    Hartung, Thomas
    Pamies, David
    FRONTIERS IN MICROBIOLOGY, 2018, 9
  • [5] iPSC-derived reactive astrocytes from patients with multiple sclerosis protect cocultured neurons in inflammatory conditions
    Kerkering, Janis
    Muinjonov, Bakhrom
    Rosiewicz, Kamil S.
    Diecke, Sebastian
    Biese, Charlotte
    Schiweck, Juliane
    Chien, Claudia
    Zocholl, Dario
    Conrad, Thomas
    Paul, Friedemann
    Alisch, Marlen
    Siffrin, Volker
    JOURNAL OF CLINICAL INVESTIGATION, 2023, 133 (13):
  • [6] Human iPSC-derived microglia - a model for neuronopathic Gaucher Disease
    Tampe, J. F.
    Crowe, J. A.
    Kokaia, Z.
    Canals, I.
    GLIA, 2023, 71 : E944 - E944
  • [7] Asiaticoside counteracts the in vitro activation of microglia and astrocytes: Innuendo for multiple sclerosis
    Madhu, Krishnadas
    Prakash, T.
    BIOMEDICINE & PHARMACOTHERAPY, 2018, 107 : 303 - 305
  • [8] Integration and functionality of human iPSC-derived microglia in a chimeric mouse retinal model
    Tang, Chun
    Zhou, Qi-Qi
    Huang, Xiu-Feng
    Ju, Ya-Yi
    Rao, Bi-Lin
    Liu, Zhi-Cong
    Jia, Yi-An
    Bai, Zhan-Pei
    Lin, Qing-Yang
    Liu, Lin
    Qu, Jia
    Zhang, Jun
    Gao, Mei-Ling
    JOURNAL OF NEUROINFLAMMATION, 2025, 22 (01)
  • [9] Pro-maturational Effects of Human iPSC-Derived Cortical Astrocytes upon iPSC-Derived Cortical Neurons
    Hedegaard, Anne
    Monzon-Sandoval, Jimena
    Newey, Sarah E.
    Whiteley, Emma S.
    Webber, Caleb
    Akerman, Colin J.
    STEM CELL REPORTS, 2020, 15 (01): : 38 - 51
  • [10] Investigating inflammatory mechanisms in iPSC-derived LRRK2 microglia
    Badanjak, K.
    Mulica, P.
    Seibler, P.
    Ali, M.
    Venegas, C.
    Pereira, S.
    Klein, C.
    Antony, P.
    Glaab, E.
    Grunewald, A.
    MOVEMENT DISORDERS, 2022, 37 : S587 - S588