Modulating the tumor-associated macrophage landscape

被引:9
|
作者
Boissonnas, Alexandre [1 ]
Combadiere, Christophe [1 ]
机构
[1] Sorbonne Univ, INSERM, CNRS, Ctr dImmunol & Malad Infectieuses, Paris, France
关键词
CHEMOKINES;
D O I
10.1038/s41590-022-01159-5
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Targeting the post-translational modification enzyme QPCTL prevents the protection of CCL2 and CCL7 from N-terminal degradation, inactivates their chemotactic function and limits the recruitment of pro-tumoral macrophages.
引用
收藏
页码:481 / 482
页数:2
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