Simultaneous Analysis to Evaluate the Quality of Insamyangpye-Tang Using High-Performance Liquid Chromatography-Photo Diode Array Detection

被引：2
|
作者：
Seo, Chang-Seob [1 ]
Lee, Mee-Young [1 ]
机构：
[1] Korea Inst Oriental Med, Herbal Med Res Div, Daejeon 34054, South Korea
来源：
APPLIED SCIENCES-BASEL | 2021年 / 11卷 / 11期
关键词：
simultaneous analysis; quality control; insamyangpye-tang; HPLC-PDA; MEDICINE;
D O I：
10.3390/app11114819
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Insamyangpye-tang (ISYPT) is a traditional medicinal formula comprised of 13 herbs and has been used in East Asia to treat lung-related diseases. However, to our knowledge, no method of analysis for its quality control has been reported. In this study, a method of analysis for quality control of ISYPT was developed using high-performance liquid chromatography. Chromatographic separation, analysis, and assay verification were performed with a distilled water-acetonitrile mobile phase system, both containing 0.1% (v/v) trifluoroacetic acid, and a Gemini C18 analytical column (4.6 mm x 250 mm, 5 mu m) using authentic standards for eight marker compounds. These marker constituents were detected simultaneously at 0.09-5.95 mg/g. The analysis method developed can be used for basic quality control of ISYPT.
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页数：8
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