Toxicological relevance of emerging contaminants for drinking water quality

被引:303
|
作者
Schriks, Merijn [1 ]
Heringa, Minne B. [1 ]
van der Kooi, Margaretha M. E. [1 ]
de Voogt, Pim [1 ,2 ]
van Wezel, Annemarie P. [1 ]
机构
[1] KWR Watercycle Res Inst, NL-3430 BB Nieuwegein, Netherlands
[2] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, NL-1018 WV Amsterdam, Netherlands
关键词
Risk assessment; Drinking water; (Provisional) drinking water guideline value; Threshold of Toxicological Concern (TTC); TERTIARY-BUTYL-ETHER; N-NITROSODIETHYLAMINE; CHRONIC INGESTION; FISCHER-344; RATS; ORAL TOXICITY; PHARMACEUTICALS; SURFACE; RISK; IDENTIFICATION; INHALATION;
D O I
10.1016/j.watres.2009.08.023
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The detection of many new compounds in surface water, groundwater and drinking water raises considerable public concern, especially when human health based guideline values are not available it is questioned if detected concentrations affect human health. In an attempt to address this question, we derived provisional drinking water guideline values for a selection of 50 emerging contaminants relevant for drinking water and the water cycle For only 10 contaminants, statutory guideline values were available Provisional drinking water guideline values were based upon toxicological literature data The maximum concentration levels reported in surface waters, groundwater and/or drinking water were compared to the (provisional) guideline values of the contaminants thus obtained, and expressed as Benchmark Quotient (BQ) values We focused on occurrence data in the downstream parts of the Rhine and Meuse river basins The results show that for the majority of compounds a substantial margin of safety exists between the maximum Concentration in surface water, groundwater and/or drinking water and the (provisional) guideline value The present assessment therefore supports the conclusion that the majority of the compounds evaluated pose individually no appreciable concern to human health (C) 2009 Elsevier Ltd All rights reserved
引用
收藏
页码:461 / 476
页数:16
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