The detection of many new compounds in surface water, groundwater and drinking water raises considerable public concern, especially when human health based guideline values are not available it is questioned if detected concentrations affect human health. In an attempt to address this question, we derived provisional drinking water guideline values for a selection of 50 emerging contaminants relevant for drinking water and the water cycle For only 10 contaminants, statutory guideline values were available Provisional drinking water guideline values were based upon toxicological literature data The maximum concentration levels reported in surface waters, groundwater and/or drinking water were compared to the (provisional) guideline values of the contaminants thus obtained, and expressed as Benchmark Quotient (BQ) values We focused on occurrence data in the downstream parts of the Rhine and Meuse river basins The results show that for the majority of compounds a substantial margin of safety exists between the maximum Concentration in surface water, groundwater and/or drinking water and the (provisional) guideline value The present assessment therefore supports the conclusion that the majority of the compounds evaluated pose individually no appreciable concern to human health (C) 2009 Elsevier Ltd All rights reserved
机构:
KWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, NetherlandsKWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
Baken, Kirsten A.
Sjerps, Rosa M. A.
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KWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, NetherlandsKWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
Sjerps, Rosa M. A.
Schriks, Merijn
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KWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
Vitens Drinking Water Co, Oude Veerweg 1, NL-8019 BE Zwolle, NetherlandsKWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
Schriks, Merijn
van Wezel, Annemarie P.
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KWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
Univ Utrecht, Copernicus Inst Sustainable Dev, Heidelberglaan 2, NL-3584 CS Utrecht, NetherlandsKWR Watercycle Res Inst, Groningenhaven 7, NL-3433 PE Nieuwegein, Netherlands
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KWR Water Res Inst, Nieuwegein, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Shaikh, S. M.
Hoondert, R.
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KWR Water Res Inst, Nieuwegein, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Hoondert, R.
Pronk, T.
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KWR Water Res Inst, Nieuwegein, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Pronk, T.
Duarte, D.
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KWR Water Res Inst, Nieuwegein, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Duarte, D.
Reus, A.
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KWR Water Res Inst, Nieuwegein, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Reus, A.
Houtman, C.
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Waterlab HWL, Haarlem, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Houtman, C.
Schriks, M.
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Vitens NV Water Co, Zwolle, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Schriks, M.
van der Oost, R.
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Waternet, Korte Ouderkerkerdijk, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
van der Oost, R.
Ezendam, J.
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Natl Inst Publ Hlth & Environm RIVM, Bilthoven, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Ezendam, J.
Pieters, R.
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Univ Utrecht, Inst Risk Assessment Sci, Utrecht, Netherlands
HU Univ Appl Sci Utrecht, Utrecht, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
Pieters, R.
Dingemans, M. M. L.
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KWR Water Res Inst, Nieuwegein, Netherlands
Univ Utrecht, Inst Risk Assessment Sci, Utrecht, NetherlandsKWR Water Res Inst, Nieuwegein, Netherlands
机构:
Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Levin, Ronnie
Villanueva, Cristina M.
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ISGlobal, Barcelona, Spain
CIBERESP, Madrid, Spain
UPF, Barcelona, Spain
IMIM Hosp del Mar, Med Res Inst, Barcelona, SpainHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Villanueva, Cristina M.
Beene, Daniel
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Univ New Mexico, Coll Pharm, Community Environm Hlth Program, Hlth Sci Ctr, Albuquerque, NM 87131 USA
Univ New Mexico, Dept Geog & Environm Studies, Albuquerque, NM 87131 USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Beene, Daniel
Cradock, Angie L.
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Harvard TH Chan Sch Publ Hlth, Boston, MA 02115 USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Cradock, Angie L.
Donat-Vargas, Carolina
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ISGlobal, Barcelona, Spain
CIBERESP, Madrid, Spain
UPF, Barcelona, SpainHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Donat-Vargas, Carolina
Lewis, Johnnye
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Univ New Mexico, Coll Pharm, Community Environm Hlth Program, Hlth Sci Ctr, Albuquerque, NM 87131 USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Lewis, Johnnye
Martinez-Morata, Irene
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Columbia Univ, Mailman Sch Publ Hlth, Dept Environm Hlth Sci, New York, NY USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Martinez-Morata, Irene
Minovi, Darya
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Union Concerned Scientists, Ctr Sci & Democracy, Washington, DC USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Minovi, Darya
Nigra, Anne E.
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Columbia Univ, Mailman Sch Publ Hlth, Dept Environm Hlth Sci, New York, NY USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Nigra, Anne E.
Olson, Erik D.
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Nat Resources Def Council, Washington, DC USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Olson, Erik D.
Schaider, Laurel A.
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Silent Spring Inst, Newton, MA USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Schaider, Laurel A.
Ward, Mary H.
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NCI, Occupat & Environm Epidemiol Branch, Div Canc Epidemiol & Genet, NIH, Rockville, MD USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA
Ward, Mary H.
Deziel, Nicole C.
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Yale Sch Publ Hlth, New Haven, CT USAHarvard TH Chan Sch Publ Hlth, Boston, MA 02115 USA