Metabolic acidosis is one of the possible causes of growth retardation in chronic renal failure (CRF). Data about the effect of metabolic acidosis on growth hormone (GPI) secretion in CRF are limited. A study was carried out on eight CRF patients, hospitalized because of severe metabolic acidosis, and eight age-matched prepubertal healthy short children. Growth hormone stimulation tests were done with L-dopa and clonidine before or during acidosis therapy and after the correction of metabolic acidosis. The levels of GH were measured by radio-immunoassay. The mean of the peaks of both tests were used for each patient and statistical significance was tested by Mann-Whitney U and Wilcoxon tests. No difference was found between the GH peaks of the two groups during acidosis and after the correction of acidosis (Wilcoxon test, P > 0.05). In view of this data it was concluded that metabolic acidosis has little effect on GH stimulation tests.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Lin, Y.-F.
Shieh, S.-D.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Shieh, S.-D.
Diang, L.-K.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Diang, L.-K.
Lin, S.-H.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Lin, S.-H.
Chyr, S.-H.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Chyr, S.-H.
Li, B.-L.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
Li, B.-L.
Lu, K.-C.
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Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, TaiwanDepartment of Medicine, National Defense Medical Center, Tri-Service General Hospital, Ting Chow Road, Taipei, Taiwan
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA
Pan, M
Meng, QH
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA
Meng, QH
Choudry, HA
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA
Choudry, HA
Karinch, AM
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA
Karinch, AM
Lin, CM
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA
Lin, CM
Souba, WW
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Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USAPenn State Univ, Milton S Hershey Med Ctr, Coll Med, Dept Surg, Hershey, PA 17033 USA