Ferrocenes in medicinal chemistry; a personal perspective

被引：52

作者：

Sansook, Supojjanee ^{[1
,2
]}

Hassell-Hart, Storm ^{[2
]}

Ocasio, Cory ^{[2
,3
]}

Spencer, John ^{[2
]}

机构：

[1] Princess Naradhiwas Univ, Fac Sci & Technol, Narathiwat 96000, Thailand

[2] Univ Sussex, Sch Life Sci, Dept Chem, Brighton BN1 9QJ, E Sussex, England

[3] Francis Crick Inst, London NW1 1AT, England

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2020年 / 905卷

基金：

英国工程与自然科学研究理事会;

关键词：

Iron; Ferrocene; Antitumor activity; Enzyme inhibitors; HISTONE DEACETYLASE INHIBITORS; BIOLOGICAL EVALUATION; METAL-COMPLEXES; CANCER; FERROQUINE; DISCOVERY; RECEPTOR; JAHA; TOOL;

D O I：

10.1016/j.jorganchem.2019.121017

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We present a short review of some of our recent work mainly targeting cancer-related oncoproteins through the development of primarily novel air- and water-stable iron-based organometallic agents. This work was presented at the recent ISBOMC19 conference at York as an invited lecture. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：5

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