Ferrocenes in medicinal chemistry; a personal perspective

被引：52
|
作者：
Sansook, Supojjanee [1 ,2 ]
Hassell-Hart, Storm [2 ]
Ocasio, Cory [2 ,3 ]
Spencer, John [2 ]
机构：
[1] Princess Naradhiwas Univ, Fac Sci & Technol, Narathiwat 96000, Thailand
[2] Univ Sussex, Sch Life Sci, Dept Chem, Brighton BN1 9QJ, E Sussex, England
[3] Francis Crick Inst, London NW1 1AT, England
来源：
JOURNAL OF ORGANOMETALLIC CHEMISTRY | 2020年 / 905卷
基金：
英国工程与自然科学研究理事会;
关键词：
Iron; Ferrocene; Antitumor activity; Enzyme inhibitors; HISTONE DEACETYLASE INHIBITORS; BIOLOGICAL EVALUATION; METAL-COMPLEXES; CANCER; FERROQUINE; DISCOVERY; RECEPTOR; JAHA; TOOL;
D O I：
10.1016/j.jorganchem.2019.121017
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
We present a short review of some of our recent work mainly targeting cancer-related oncoproteins through the development of primarily novel air- and water-stable iron-based organometallic agents. This work was presented at the recent ISBOMC19 conference at York as an invited lecture. (C) 2019 Elsevier B.V. All rights reserved.
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页数：5
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